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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-RHEB Polyclonal Antibody

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货号 TMAB-12236

Anti-RHEB Polyclonal Antibody 是一种 Rabbit 抗体，靶向 RHEB。Anti-RHEB Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-RHEB Polyclonal Antibody

Anti-RHEB Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-12236

Anti-RHEB Polyclonal Antibody 是一种 Rabbit 抗体，靶向 RHEB。Anti-RHEB Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-RHEB Polyclonal Antibody is a Rabbit antibody targeting RHEB. Anti-RHEB Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse,Rat (predicted:Human,Chicken,Cow,Horse)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell membrane; Lipid-anchor; Cytoplasmic side.
组织特异性Ubiquitous. Highest levels observed in skeletal and cardiac muscle.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Rheb (Ras homolog enriched in brain) is an evolutionarily conserved member of the Ras family of small GTP binding proteins originally found to be rapidly induced by synaptic activity in the hippocampus following seizure. While it is expressed at relatively high levels in the brain, Rheb is widely expressed in other tissues and may be induced by growth factor stimulation. Similar to other family members, Rheb triggers activation of the Raf-MEK-MAPK pathway. Biochemical and genetic studies demon-strate that Rheb has an important role in regulating the insulin/Target of rapamycin (TOR) signaling pathway. TOR is a serine/threonine protein kinase that acts as a sensor for ATP and amino acids, balancing the availability of nutrients with protein translation and cell growth. A dimeric protein complex termed TSC1/TSC2 indirectly inhibits TOR activity by inhibiting Rheb via the GAP activity of TSC2.
抗原信息
免疫原
KLH conjugated synthetic peptide: human RHEB
抗原种属
Human
基因名称
RHEB
基因ID
6009
蛋白名称
GTP-binding protein Rheb
Uniprot ID
Q15382
功能
Stimulates the phosphorylation of S6K1 and EIF4EBP1 through activation of mTORC1 signaling. Activates the protein kinase activity of mTORC1. Has low intrinsic GTPase activity.
化学信息
分子量Theoretical: 20 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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