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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-PURB Polyclonal Antibody

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货号 TMAB-11949

Anti-PURB Polyclonal Antibody 是一种 Rabbit 抗体，靶向 PURB。Anti-PURB Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-PURB Polyclonal Antibody

Anti-PURB Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-11949

Anti-PURB Polyclonal Antibody 是一种 Rabbit 抗体，靶向 PURB。Anti-PURB Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-PURB Polyclonal Antibody is a Rabbit antibody targeting PURB. Anti-PURB Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human,Mouse,Rat (predicted:Cow,Rabbit,Sheep)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus.
组织特异性Expressed in myocardium of heart failure patients.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4.
浓度1mg/ml
研究背景This gene product is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of this gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia. [provided by RefSeq, Jul 2008]
抗原信息
免疫原
KLH conjugated synthetic peptide: human PURB
抗原种属
Human
基因名称
PURB
基因ID
5814
蛋白名称
Transcriptional activator protein Pur-beta
Uniprot ID
Q96QR8
功能
Has capacity to bind repeated elements in single-stranded DNA such as the purine-rich single strand of the PUR element located upstream of the MYC gene. Plays a role in the control of vascular smooth muscle (VSM) alpha-actin gene transcription as repressor in myoblasts and fibroblasts. Participates in transcriptional and translational regulation of alpha-MHC expression in cardiac myocytes by binding to the purine-rich negative regulatory (PNR) element. Modulates constitutive liver galectin-3 gene transcription by binding to its promoter. May play a role in the dendritic transport of a subset of mRNAs.
化学信息
分子量Theoretical: 33 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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