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Anti-Phospho-SIRT1 (Ser47) Polyclonal Antibody 2
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产品编号 TMAC-03759
别名 sirtuin 1, SIRT1 (p-Ser47), SIRT1 (p-S47), SIR2L1, p-SIRT1 (Ser47), p-SIRT1 (S47)
Anti-Phospho-SIRT1 (Ser47) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-SIRT1 (Ser47)。Anti-Phospho-SIRT1 (Ser47) Polyclonal Antibody 可用于 WB。
Anti-Phospho-SIRT1 (Ser47) Polyclonal Antibody 2
Anti-Phospho-SIRT1 (Ser47) Polyclonal Antibody 2
还可以产品编号 TMAC-03759 别名 sirtuin 1, SIRT1 (p-Ser47), SIRT1 (p-S47), SIR2L1, p-SIRT1 (Ser47), p-SIRT1 (S47)
Anti-Phospho-SIRT1 (Ser47) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-SIRT1 (Ser47)。Anti-Phospho-SIRT1 (Ser47) Polyclonal Antibody 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,490 | 5日内发货 | |
| 100 μL | ¥ 2,240 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
化学信息
| 产品描述 | Anti-Phospho-SIRT1 (Ser47) Polyclonal Antibody is a Rabbit antibody targeting Phospho-SIRT1 (Ser47). Anti-Phospho-SIRT1 (Ser47) Polyclonal Antibody can be used in WB. |
| 别名 | sirtuin 1, SIRT1 (p-Ser47), SIRT1 (p-S47), SIR2L1, p-SIRT1 (Ser47), p-SIRT1 (S47) |
| Ig Type | IgG |
| 交叉反应 | Human |
| 验证活性 | 1. Western blot analysis of extracts from JK tissue using SirT1 (Phospho-Ser47) antibody TMAC-03759. The lane on the right is treated with the antigen-specific peptide. |
| 应用 | |
| 推荐剂量 | WB: 1:500-1000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Polyclonal Antibody |
| 纯化方式 | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| 性状 | Liquid |
| 缓冲液 | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| 研究背景 | NAD-dependent protein deacetylase that links transcriptional regulation directly to intracellular energetics and participates in the coordination of several separated cellular functions such as cell cycle, response to DNA damage, metobolism, apoptosis and autophagy. Can modulate chromatin function through deacetylation of histones and can promote alterations in the methylation of histones and DNA, leading to transcriptional repression. Deacetylates a broad range of transcription factors and coregulators, thereby regulating target gene expression positively and negatively. |
| 偶联 | Unconjugated |
| 其他可选修饰符 | Phospho |
| 免疫原 | Peptide sequence around phosphorylation site of serine 47(E-R-S(p)-P-G) derived from Human SirT1 |
| 抗原种属 | human |
| Uniprot ID |
| 分子量 | Actual: 110 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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