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顶部生物活性储存和溶解信息计算器

Anti-NME1 Antibody-PE (1U277)

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产品编号 TMAY-01935P

别名 NME/NM23 nucleoside diphosphate kinase 1, NM23-H1, NM23, NDPK-A, NDPKA, NDKA, NBS, NB, GAAD, AWD

Anti-NME1 Antibody-PE (1U277) 是一种 PE-conjugated Mouse 抗体，靶向 NME1。Anti-NME1 Antibody-PE (1U277) 可用于 FCM。

Anti-NME1 Antibody-PE (1U277)

Anti-NME1 Antibody-PE (1U277)

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Rating icon 还可以
产品编号 TMAY-01935P 别名 NME/NM23 nucleoside diphosphate kinase 1, NM23-H1, NM23, NDPK-A, NDPKA, NDKA, NBS, NB, GAAD, AWD

Anti-NME1 Antibody-PE (1U277) 是一种 PE-conjugated Mouse 抗体，靶向 NME1。Anti-NME1 Antibody-PE (1U277) 可用于 FCM。

规格价格库存数量
25 T
¥ 1,090
5日内发货
100 T
¥ 2,185
5日内发货
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产品介绍

生物活性
产品描述
Anti-NME1 Antibody-PE (1U277) is a PE-conjugated Mouse antibody targeting NME1. Anti-NME1 Antibody-PE (1U277) can be used in FCM.
别名NME/NM23 nucleoside diphosphate kinase 1, NM23-H1, NM23, NDPK-A, NDPKA, NDKA, NBS, NB, GAAD, AWD
Ig Type
Mouse IgG1
克隆号
1U277
交叉反应
Human
特异性
Human NME1
验证活性
Flow cytometric analysis of Human NME1 expression in HeLa cells. The cells were treated according to manufacturer’s manual (BD Pharmingen™ Cat. No. 554714), and then stained with PE Mouse anti-NME1. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.
应用FCM
推荐剂量
5 μl/Test, 0.1 mg/ml
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human NME1 / NDKA (rh NME1 / NDKA; TMPY-04467; NP_000260.1; Ala 2-Glu 152) and conjugated with PE under optimum conditions, the unreacted PE was removed.
纯化方式Protein A
性状Liquid
缓冲液PBS solution containing 0.5% BSA and 0.03%ProClin300
研究背景NME1, also known as Nucleoside Diphosphate Kinase A (NDK-A), or NM23-H1, belongs to the NDK family. NM23-H1 is known to have a metastasis suppressive activity in many tumor cells. Recent studies have shown that the interacting proteins with NM23-H1 which mediate cell proliferation, may act as modulators of the metastasis suppressor activity. The interacting proteins with NM23-H1 can be classified into 3 groups. The first group of proteins can be classified as upstream kinases of NM23-H1 such as CKI and Aurora-A/STK15. The second group of proteins acts as downstream effectors for the regulation of specific gene transcriptions, GTP-binding protein functions, and signal transduction in the Erk signal cascade. The third group of proteins can be classified as bi-directionally influencing binding partners of NM23-H1. As a result, the interactions with NM23-H1 and binding partners have implications in the biochemical characterization involved in metastasis and tumorigenesis. NDKA is increased in human postmortem cerebrospinal fluid (CSF), a model of global brain insult, suggesting that measurement in CSF and, more importantly, in plasma may be useful as a biomarker of stroke. Additionally, NM23-H1 significantly reduces metastasis without effects on primary tumor size and was the first discovered metastasis suppressor gene.
偶联与修饰
偶联
PE
其他可选修饰符
Unconjugated/FITC
可提供抗体种类
3
抗原信息
免疫原
Recombinant Protein: Human NME1 / NDKA protein (TMPY-04467)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight.
运输方式Shipping with blue ice.

计算器

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关键词

NM-23NM 23

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