quinolactacin a

Quinolactactin A is a quinolone fungal metabolite originally isolated from Penicillium. It inhibits TNF production induced by LPS in murine peritoneal macrophages (IC50 = 12.2 μg/ml). It is not active against a variety of bacteria, fungi, and yeasts. Quinolactacin A is a mixture of quinolactacin A1 and A2.

Quinolactacin A1 是一种有效的乙酰胆碱酯酶 (AChE) 抑制剂，可从Penicillium citrinum 中得到。Quinolactacin A1 可用于阿尔茨海默病的研究。