ppa 1

(D)-PPA 1 TFA为一种抗水解D肽拮抗剂，同时也是有效的PD-1 PD-L1抑制剂。该化合物与PD-1结合亲和力达0.51 μM，且在体内外实验中表现有效。

PD-1/PD-L1 interaction inhibitor. Binds to PD-L1 (Kd = 0.51 μM). Inhibits interaction at 1 mg/mL in flow cytometry. Inhibits tumor growth and prolongs survival time of mice in vivo.