pf 4479745

PF-4479745 ia a potent and selective agonist of 5-HT2C receptor.

EXP-561 monohydrate is an investigational drug that acts as an inhibitor of the reuptake of serotonin, dopamine, and norepinephrine.

PF-04479745, also known as PF-4479745, is a potent and selective 5-HT2C agonist (EC50 = 10 nM). PF-4479745 displayed robust pharmacology in a preclinical canine model of stress urinary incontinence (SUI) and no measurable functional agonism at the key selectivity targets 5-HT2A and 5-HT2B in relevant tissue-based assay systems.