ot antagonist 1

OT antagonist 1 is a potent and selective antagonist of Oxytocin(Ki of 50 nM)

OT antagonist 1 demethyl derivative, a demethyl derivative of OT antagonist 1, is a selective Oxytocin antagonist with a Ki of 50 nM.

OT-R antagonist 1 inhibits oxytocin-evoked intracellular Ca2+ mobilization (IC50 = 8 nM). OT-R antagonist 1 is a new effective and selective nonpeptide low molecular weight OT-R antagonist.

OT-R agonist 1 TFA (compound 5) 是一种作为催产素受体 (oxytocin receptor) 激动剂的化合物，其EC50值为0.39 nM。它也表现出V1A拮抗剂的活性，EC50值为2432 nM，可用于中枢神经系统疾病的研究。