midostaurind5

Midostaurin-D5 is a deuterium labeled Midostaurin.

3-Hydroxy Midostaurin-D5 (CGP52421-D5) is a deuterium-labeled 3-Hydroxy Midostaurin which is a metabolite of PKC412. PKC412 effectively inhibits FMS-like tyrosine kinase-3 (FLT3) autophosphorylation (IC50s: 132 nM and 9.8 μM in culture medium and plasma).

O-Desmethyl Midostaurin-d5 是 O-Desmethyl Midostaurin 的氘代化合物。