lydicamycin

Lydicamycin是从一种被鉴定为溶性链霉菌的放线菌菌株的发酵液中分离出的新型抗生素，Lydicamycin对革兰氏阳性菌和某种酵母菌有活性，但对革兰氏阴性菌无活性。[2]

TPU-0037C is a metabolite of the marine actinomycete S. platensis that is structurally similar to lydicamycin . It is active against Gram-positive bacteria (MICs = 0.39-3.13 μg ml), including methicillin-resistant S. aureus strains (MIC = 3.13 μg ml), but is ineffective against Gram-negative bacteria (MICs = >50 μg ml).

TPU-0037A is an antibiotic and a congener of lydicamycin . It inhibits the growth of Gram-positive bacteria, including methicillin-resistant S. aureus (MRSA), B. subtilis, and M. luteus (MICs = 1.56-12.5 μg ml), but not Gram-negative E. coli, P. mirabilis, P. vulgaris, or P. aeruginosa strains (MICs = >50 μg ml).