ZD7114, also known as ICI-D7114, is a selective adrenoceptor agonist of brown fat and thermogenesis. ICID7114 stimulates thermogenesis at doses that have little effect on beta 1 or beta 2 adrenoceptors. Treatment with ICID7114 activates BAT and thermogenesis even in species and situations where the intrinsic capacity is low. ICID7114 has beneficial effects in animal models of obesity and disturbed glucose and lipid homeostasis.