FTSDVSKQMEEEAVRLFIEWLKNGGPSSGAPPPS is an Exendin-4 peptide derivative.Exendin-4 peptide derivatives are structurally derived from Exendin-4 and may relates to dual GLP-1 glucagon receptor agonists.
Tryptophan-cholic acid (Trp-CA) 是一种微生物氨基酸结合胆汁酸(MABAs),是MRGPRE(Mas-related GPCR family member E)的内源性配体和激动剂,进而诱导GLP-1分泌。Tryptophan-cholic acid可以改善糖尿病小鼠的葡萄糖耐量,可用于研究2型糖尿病。