exendin-4

Exendin-4 (Exenatide) 是一种长效的 glucagon-likepeptide-1 受体激动剂(IC50: 3.22 nM)，是一种由 39 个氨基酸组成的多肽。

Exendin-4 acetate 是一种长效的 glucagon-likepeptide-1 受体激动剂(IC50:3.22 nM)，是一种由39个氨基酸组成的多肽。。

Exendin-4 peptide derivative acetate is an acetate salt of Exendin-4 peptide derivative.

FTSDVSKQMEEEAVRLFIEWLKNGGPSSGAPPPS is an Exendin-4 peptide derivative.Exendin-4 peptide derivatives are structurally derived from Exendin-4 and may relates to dual GLP-1 glucagon receptor agonists.

Exenatide (Extendin-4) 是一种胰高血糖素样蛋白 1 (GLP-1) 受体激动剂。

Exendin-4 (3-39) 是一种肽。Exendin-4 (3-39) 是 Exendin-4 的截断形式，缺少前两个氨基酸。Exendin-4 是一种有效的 GLP-1r 激动剂。Exendin-4 (3-39) 和 Exendin-4 可用于糖尿病和下丘脑-垂体-肾上腺 (HPA) 轴的研究。

Des His1, Glu8 Exendin-4 是一种胰高血糖素样肽-1 受体 (GLP-1-R) 拮抗剂，可调节血糖。Des His1, Glu8 Exendin-4 用于研究糖尿病和肥胖。

Exenatide acetate 是由39个氨基酸组成的多肽激素。Exendin-4 acetate是一种glucagon-like peptide-1(GLP-1)受体激动剂，IC50=3.22 nM，可用于胰岛素瘤和2型糖尿病。Exendin acetate可以促进体外HUVECs的迁移、发芽和NO生成，对MCF-7具有细胞毒性，对小鼠后肢模型的缺血性损伤具有保护作用。

Tryptophan-cholic acid (Trp-CA) 是一种微生物氨基酸结合胆汁酸（MABAs），是MRGPRE(Mas-related GPCR family member E)的内源性配体和激动剂，进而诱导GLP-1分泌。Tryptophan-cholic acid可以改善糖尿病小鼠的葡萄糖耐量,可用于研究2型糖尿病。

Exendin-3/4 (64-86) 是一种多肽。

KQMEEEAVRLFIEWLKNGGPSSGAPPPS is a Exendin-4 peptide derivative. Exendin-4 is a pure GLP-1 receptor agonist. Exendin-4 peptide derivatives are structurally derived from Exendin-4 and may relates to dual GLP-1 glucagon receptor agonists. Their medical use, for example in the treatment of disorders of the metabolic syndrome, including diabetes and obesity, as well as for reduction of excess food intake. These dual GLP-1 glucagon receptor agonists show reduced activity on the GIP receptor to reduce the risk of hypoglycemia[1]. [1]. US20150315260 A1

FTSDVSKQMEEEAVRLFIEWLKNGGPSSGAPPPS 是Exendin-4多肽衍生物。

GTFTSDVSKQMEEEAVRLFIEWLKNGGPSSGAPPPS 是 Exendin-4多肽衍生物。

Exendin-3 4 (59-86) is a derivative of the Exendin-4 peptide.

{Val1}- exendin-3/4 is the first n-terminal 1-28 residue of exendin-4 peptide.

SDV-Exendin-3 4 is a 32-amino acid peptide. Derived from the salivary gland of the Gila monster (Heloderma suspectum), this peptide is a ligand for the GLP-1 receptor, playing a key role in glucose metabolism and insulin secretion. It exhibits significant potential for therapeutic applications in diabetes management.

Albenatide is a modified analog of exendin 4 conjugated to recombinant human albumin.