epsilon (gamma glutamyl) lysine

Epsilon-(gamma-glutamyl)-lysine is an N(6)-acyl-L-lysine derivative that forms bonds between extracellular matrix (ECM) components with the assistance of the enzyme tissue transglutaminase (tTg). These bonds are implicated in the pathogenesis of certain diseases like non-diabetic kidney and glaucoma filtration.

Epsilon-(gamma-glutamyl)-lysine acetate (17105-15-6 Free base) 是一种 N(6)-酰基-L-赖氨酸衍生物，可在组织转谷氨酰胺酶的帮助下在细胞外基质 (ECM) 成分之间形成键 （tTg）。 这些键与某些疾病（如非糖尿病肾病和青光眼滤过）的发病机制有关。

Epsilon-(gamma-glutamyl)-lysine (H-Glu(H-Lys-OH)-OH) TFA 为 N(6)-acyl-L-lysine 的衍生物，其在特定疾病中（如非糖尿病肾病、青光眼）通过组织转谷氨酰胺酶(tTg)作用，促进ECM成分间Epsilon-(gamma-glutamyl)-lysine键形成，从而增加。