cnv dopamine

CNV Dopamine is a carboxynitroveratryl (CNV)-caged dopamine; releases dopamine upon ultraviolet light stimulation (365 nm). Induces dopaminergic currents upon photolysis in brain slices expressing wild-type or GFP-labeled D2receptors. Displays no decrease in current (rundown) with UV light flash duration of up to 100 ms. Pharmacologically inactive prior to photolysis.

CNV-dopamine 是一种可以通过光激活的、选择性针对 D2 受体 (D2 receptor) 的激动剂。它能够激活 D2 受体，并诱导 G 蛋白偶联的内向整流钾 (GIRK) 电流。CNV-dopamine 有潜力用于帕金森病和成瘾等疾病的研究。