avian

Cadherin Peptide, avian Acetate 是一种肽，序列为 Leu-Arg-Ala-His-Ala-Val-Asp-Val-Asn-Gly-NH2。钙粘蛋白是一类 1 型跨膜蛋白。

Harpactira Baviana Venom (Baboon Tarantula Venom) 是一种蜘蛛毒液，能够从皇帝巴布蜘蛛蜘蛛中获得。Harpactira Baviana Venom 可以调节 NaV1.8和诱导痛觉过敏。

(S)-(-)-O-Demethylbuchenavianine (Compound (S)-(−)-1) 作为一种黄酮生物碱，展现出对CDK的有效抑制作用，其针对CDK1和CDK5的IC50值分别为0.03μM和0.05μM。

(R)-(+)-O-Demethylbuchenavianine 是一种针对细胞周期蛋白依赖性激酶 (CDK) 的抑制剂，有效抑制多种激酶，包括 CDK1、CDK5、糖原合酶激酶 3 (GSK3)、cdc2 样激酶 (CLK1) 以及双特异性酪氨酸磷酸化调节激酶 1A (DYRK1A)。其半抑制浓度 (IC50) 分别为 1.1、0.95、>10、>10 和 >10 μM。

(E)-Cinnamamide (trans-Cinnamamide) 是 Cinnamamide 的活性较低的异构体，Cinnamamide 是一种有效的非致命化学驱虫剂，适用于减少鸟类害虫的损害。

N-Acetyl-DL-methionine 是内源性代谢产物的一种。

MBX2329 是一种流感病毒抑制剂，能特异性地抑制血凝素介导的病毒进入，HIV HA(H5) 的 IC90值为8.6 μM。它能够有效地抑制多种甲型流感病毒。

Laninamivir (R 125489) 是一种流感神经氨酸酶抑制剂，对流感病毒 H12N5 NA (N5)，pH1N1 N1 NA (p09N1) 和 A RI 5+ 1957 H2N2 N2 (p57N2) 的 IC50值分别为 0.90 nM、1.83 nM 和 3.12 nM。

6′SLN, 作为主要的EVs蛋白质糖基化形式，是癌症相关细胞外囊泡 (EVs) 表面具有特征性的糖基。此外，作为唾液酸的衍生物，6′SLN 能与人类及禽流感病毒株的血凝素 (HAs) 交互作用，因此在抗流感药物的开发中具有潜在应用价值。

CL385319 is a potent inhibitor of H5N1 avian influenza A virus infection by blocking viral entry. CL-385319 is effective in inhibiting infection of highly pathogenic H5N1 influenza A virus in Madin-Darby Canine Kidney (MDCK) cells with an IC50 of 27.03±2.

Endochin is an experimental antimalarial. Endochin and analogues thereof are causal prophylactic and potent erythrocytic stage agents in avian models.

Avilamycin A is an antibiotic.1 It is active against veterinary isolates of C. perfringens (MICs = ≤0.06-0.5 mg/L) and B. hyodysenteriae (MICs = 12.5-100 μg/ml).1,2 Dietary administration of avilamycin A (15 and 30 ppm) reduces mortality in a broiler cockerel model of C. perfringens infection.3 Formulations containing avilamycin A have been used in the prevention of necrotic enteritis in livestock. |1. Watkins, K.L., Shryock, T.R., Dearth, R.N., et al. In-vitro antimicrobial susceptibility of Clostridium perfringens from commercial turkey and broiler chicken origin. Vet. Microbiol. 54(2), 195-200 (1997).|2. Uezato, K., Kinjo, E., and Adachi, Y. In vitro susceptibility of 21 antimicrobial agents to 37 isolates of Brachyspira hyodysenteriae isolated from pigs in Okinawa Prefecture. J. Vet. Med. Sci. 66(3), 307-309 (2004).|3. Paradis, M.A., McMillan, E., Bagg, R., et al. Efficacy of avilamycin for the prevention of necrotic enteritis caused by a pathogenic strain of Clostridium perfringens in broiler chickens. Avian Pathol. 45(3), 365-369 (2016).

KIN1148 是一种新型小分子佐剂，是IRF3激动剂，用于增强流感疫苗效率。

Y27632 is a selective ROCK inhibitor, which inhibits ET-1-induced increases in natriuretic peptide production, cell size, protein synthesis, and myofibrillar organization. Y27632 prevents dimethylnitrosamine-induced hepatic fibrosis in rats, increases apoptosis and disrupts the actin cortical mat in embryonic avian corneal epithelium, affects initial heart myofibrillogenesis in cultured chick blastoderm, promotes the proliferation and cell cycle progression of cultured astrocyte from spinal cord.

EIDD-2749 (4'-FlU) 是核糖核苷类似物，是一种可口服的 RdRp 抑制剂，具有光谱的抗病毒活性，可中断呼吸道合胞病毒和 SARS-CoV-2 复制。EIDD-2749可减轻大流行性人类和高致病性禽流感病毒的致命感染。

[Asp5]-Oxytocin acetate 是一款功能强大的5位 (5-position) 神经垂体激素类似物，能引发体外大鼠子宫收缩，其效果可被 Mg2+ 增强。此化合物展现出在大鼠子宫收缩、禽血管抑制及大鼠抗利尿作用方面的活性。

Xenopsin-Related Peptide 2 (XP-2)，作为Xenopsin在鸟类中的对应物，具有诱导分离大鼠肥大细胞释放组胺的能力，其效力与合成Bradykinin相媲美。

Baicalin methyl ester 是黄芩苷根的一种成分。

Asebotin shows anti-influenza A virus activity, it also possesses potent antiviral activity (100% inhibition at the concentration of 1 ug mL) against highly pathogenic avian influenza strain H5N1. Asebotin can inhibit the proliferation of murine B cells.

Platycoside A has hemolytic activity and adjuvant potential on the immune responses to Newcastle disease virus-based recombinant avian influenza vaccine. It induces the IgG and IgG1 antibody responses in the immunized mice.

Platyphyllonol 来自赤杨树皮，对 KBNP-0028 (H9N2) 禽流感病毒表现出中等活性。

[Gln8] Luteinizing hormone releasing hormone ([Gln8] LH-RH), Avian hypothalamic peptide that stimulates release of gonadotropins from anterior pituitary, thus regulating reproductive functions.

[Gln8]-C517 (LH-RH), chicken acetate(47922-48-5 free base) 是一种鸟类下丘脑肽，可刺激垂体前叶释放促性腺激素，从而调节生殖功能。

RFRP-3, mouse 是一种禽类促性腺激素抑制激素 (GnIH) 的功能同源物，与GPR147结合。它通过抑制 FSHR 和类固醇生成的关键酶 (P450scc、3β-HSD、StAR) 减少Progesterone 的合成。RFRP-3 (mouse) 还可诱导细胞凋亡 (Apoptosis)，伴随p53 增加，并抑制ERK信号通路。RFRP-3, mouse 可应用于卵泡发育研究。