5-Fluorouracil-13C,15N2 is intended for use as an internal standard for the quantification of 5-flurouracil by GC- or LC-MS. 5-Fluorouracil (T0984) is a pyrimidine analog that irreversibly inhibits thymidylate synthase,blocking the synthesis of thymidine which is required for DNA synthesis. Intracellular metabolites of 5-fluorouracil exert cytotoxic effects by either inhibiting thymidylate synthetase,or through incorporation into RNA and DNA,ultimately initiating apoptosis.

5-Fluorouracil-13C,15N2 (Standard) 是 5-Fluorouracil-13C,15N2 的标准品，适用于定量分析、质量控制及生化实验等相关研究。5-Fluorouracil-13C,15N2 用于通过气相色谱-质谱法或液相色谱-质谱法对 5-氟尿嘧啶进行定量分析时作为内标物。5-Fluorouracil是一种嘧啶类似物，它不可逆地抑制胸苷酸合成酶，从而阻断胸苷的合成，而胸苷是 DNA 合成所必需的。5-Fluorouracil的细胞内代谢产物通过抑制胸苷酸合成酶或通过掺入 RNA 和 DNA 形成细胞毒性作用，最终引发细胞凋亡。