趋化因子

趋化因子是诱导白细胞以及其他细胞类型（包括内皮细胞和上皮细胞）定向运动的细胞分泌的细胞因子或信号蛋白家族。除了在激活宿主免疫反应中发挥重要作用外，趋化因子对生物过程也很重要，包括形态发生和伤口愈合，以及癌症等疾病的发病机制。一些趋化因子被认为是促炎的，可以在免疫反应期间诱导，将免疫系统的细胞募集到感染部位，而另一些趋化因子被认为是稳态的，并且在组织维持或发育的正常过程中参与控制细胞的迁移。趋化因子分为四个主要亚家族：CXC、CC、CX3C 和 C。所有趋化因子都通过与称为趋化因子受体的 G 蛋白连接的跨膜受体相互作用来发挥其生物学效应。

Cat. No.	Product Name / Synonyms	Species	Expression System
TMPJ-00005	CCL3 Protein, Human, Recombinant CCL3 Protein, Human, Recombinant	Human	E. coli
TMPJ-00005	Human Chemokine (C-C Motif) Ligand 3 (CCL3) is a small cytokine belonging to the CC chemokine family. CCL3 is primarily expressed in T cells, B cells, and monocy...
TMPJ-00006	CXCL1 Protein, Mouse, Recombinant (His) CXCL1 Protein, Mouse, Recombinant (His)	Mouse	Human Cells
TMPJ-00006	Growth-regulated alpha protein (CXCL1,KC), is a member of the alpha chemokine subfamily, was initially identified as an immediate early gene induced in mouse fib...
TMPJ-00008	CXCL10 Protein, Human, Recombinant (hFc & His) CXCL10 Protein, Human, Recombinant (hFc & His)	Human	Human Cells
TMPJ-00008	Human C-X-C Motif Chemokine Ligand 10 (CXCL10) is a non-ELR chemokine secreted by various cell types, such as monocytes, endothelial cells and fibroblasts, in re...
TMPJ-00009	CCL2 Protein, Human, Recombinant CCL2 Protein, Human, Recombinant	Human	E. coli
TMPJ-00009	The chemokine (C-C motif) ligand 2 (CCL2), also known as monocyte chemoattractant protein (MCP)-1 and small inducible cytokine A2 (SCYA2)), is a small cytokine t...
TMPJ-00010	CCL8 Protein, Human, Recombinant CCL8 Protein, Human, Recombinant	Human	E. coli
TMPJ-00010	Human Chemokine (C-C Motif) Ligand 8 (CCL8) is produced by human MG63 osteosarcoma cells. CCL8 shares 62% and 58% amino acid sequence identity with MCP-1 and MCP...
TMPJ-00011	CXCL2 Protein, Mouse, Recombinant CXCL2 Protein, Mouse, Recombinant	Mouse	E. coli
TMPJ-00011	C-X-C motif chemokine 2 (CXCL2,MIP-2) belongs to the intercrine alpha (chemokine CxC) family. It was originally identified as a heparin-binding protein secreted ...
TMPJ-00012	CXCL4 Protein, Human, Recombinant (His) CXCL4 Protein, Human, Recombinant (His)	Human	Human Cells
TMPJ-00012	Human Chemokine (C-X-C motif) Ligand 4 (CXCL4) is expressed in megakaryocytes and stored in the alpha-granules of platelets. CXCL4 contains several heparin-bindi...
TMPJ-00018	CCL16 Protein, Human, Recombinant CCL16 Protein, Human, Recombinant	Human	E. coli
TMPJ-00018	CCL16 is a member of CC chemokine family. CCL16 cDNA encodes a 120 amino acid peptide along with a 23 amino acids signal peptide that is cleaved to generate 97 a...
TMPJ-00019	CCL28 Protein, Human, Recombinant CCL28 Protein, Human, Recombinant	Human	E. coli
TMPJ-00019	Chemokine (C-C Motif) Ligand 28 (CCL28) is a novel chemokine that shares the most homology with CCL27/CTACK. CCL28 shows chemotactic activity for resting CD4, CD...
TMPJ-00028	CCL2 Protein, Mouse, Recombinant CCL2 Protein, Mouse, Recombinant	Mouse	E. coli
TMPJ-00028	C-C motif chemokine 2 (CCL2) is a member of the C-C or β chemokine family. Mouse CCL2 shares 82% amino acid (aa) identity with rat CCL2 over the entire sequence,...
TMPJ-00591	CCL8 Protein, Human, Recombinant (His) CCL8 Protein, Human, Recombinant (His)	Human	Human Cells
TMPJ-00591	Human Chemokine (C-C Motif) Ligand 8 (CCL8) is produced by human MG63 osteosarcoma cells. CCL8 shares 62% and 58% amino acid sequence identity with MCP-1 and MCP...
TMPJ-00673	CX3CL1/Fractalkine Protein, Mouse, Recombinant (His) CX3CL1/Fractalkine Protein, Mouse, Recombinant (His)	Mouse	Human Cells
TMPJ-00673	Fractalkine(CX3CL1) is a single-pass type I membrane protein and belongs to the intercrine delta family. It consists of an extracellular NH2-terminal domain, a m...
TMPJ-00760	CXCL7 Protein, Human, Recombinant CXCL7 Protein, Human, Recombinant	Human	E. coli
TMPJ-00760	Human Chemokine (C-X-C motif) Ligand 7 (CXCL7), also known as neutrophil activating peptide 2 (NAP-2), is a member of the CXC chemokines containing an ELR domain...
TMPJ-00831	CCL3 Protein, Mouse, Recombinant (His) CCL3 Protein, Mouse, Recombinant (His)	Mouse	E. coli
TMPJ-00831	C-C Motif Chemokine 3 (MIP-1 alpha,CCL3 ) is a member of the beta or CC subfamily of chemokines and is closely related to CCL4/MIP-1 beta. CCL3 expression can be...
TMPJ-00852	CCL2 Protein, Rat, Recombinant (His) CCL2 Protein, Rat, Recombinant (His)	Rat	Human Cells
TMPJ-00852	Monocyte chemoattractant protein 1 (MCP-1), also called CCL2, is a member of the beta (C-C) subfamily of chemokines that is a chemoattractant for monocytes and b...
TMPJ-00873	CCL3L1 Protein, Human, Recombinant (His) CCL3L1 Protein, Human, Recombinant (His)	Human	Human Cells
TMPJ-00873	C-C Motif Chemokine 3-Like 1 (CCL3L1) is a secreted protein that belongs to the intercrine beta (chemokine CC) family. CCL3L1 is a ligand for CCR1, CCR3 and CCR5...
TMPJ-00884	CXCL9 Protein, Mouse, Recombinant (His) CXCL9 Protein, Mouse, Recombinant (His)	Mouse	Human Cells
TMPJ-00884	Chemokine (C-X-C motif) ligand 9 (CXCL9, MIG), is a small cytokine belonging to the CXC chemokine family. CXCL9 functions as one of the three ligands of chemokin...
TMPJ-00952	CXCL12 Protein, Mouse, Recombinant CXCL12 Protein, Mouse, Recombinant	Mouse	E. coli
TMPJ-00952	Mouse Cxcl12 is a secreted and highly conserved protein which belongs to the intercrine alpha (chemokine CxC) family.CXCL12 is widely expressed in various organs...
TMPJ-00974	XCL1 Protein, Human, Recombinant (hFc & His) XCL1 Protein, Human, Recombinant (hFc & His)	Human	Human Cells
TMPJ-00974	Lymphotactin is a secreted protein which belongs to the intercrine gamma family. It is also a member of the XC chemokine family. XCL1 is found in spleen with hig...
TMPJ-00993	CCL5 Protein, Rat, Recombinant (E. coli, His) CCL5 Protein, Rat, Recombinant (E. coli, His)	Rat	E. coli
TMPJ-00993	C-C motif chemokine 5(CCL5) is a β-chemokine that plays a primary role in the inflammatory immune response by means of its ability to attract and activate leukoc...