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IL-5 Protein, Human, Recombinant

IL-5 Protein, Human, Recombinant

产品编号 TMPY-03915
别名: TRF, 白介素, EDF, interleukin 5, IL-5, 白细胞介素

Interleukin 5 (IL-5) is a member of the interleukin family with a length of 115 amino acids. Interleukins are a group of cytokines (secreted proteins/signaling molecules) that were first seen to be expressed by white blood cells (leukocytes) and has been found in a wide variety of body cells. Interleukin 5 or IL-5 is produced by T helper-2 cells and mast cells. It helps to stimulate B cell growth and increase immunoglobulin secretion and is considered a key mediator in eosinophil activation. Interleukin 5 (IL-5) has long been associated with several allergic diseases, including allergic rhinitis and asthma. Growth in the number of circulating, airway tissue, and induced sputum eosinophils have been observed in patients with these diseases. IL-5 also had something with the terminally differentiated granulocyte eosinophils. IL-5 was originally found as an eosinophil colony-stimulating factor. It has been proved to be a major regulator of eosinophil accumulation in tissues and can modulate eosinophil behavior at every stage from maturation to survival.

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IL-5 Protein, Human, Recombinant Chemical Structure
IL-5 Protein, Human, Recombinant, CAS N/A
规格 价格/CNY 货期 数量
5 μg ¥ 560 现货
10 μg ¥ 910 5日内发货
20 μg ¥ 1,470 5日内发货
50 μg ¥ 2,750 5日内发货
100 μg ¥ 4,430 5日内发货
产品目录号及名称: IL-5 Protein, Human, Recombinant (TMPY-03915)
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参考文献
产品描述 Interleukin 5 (IL-5) is a member of the interleukin family with a length of 115 amino acids. Interleukins are a group of cytokines (secreted proteins/signaling molecules) that were first seen to be expressed by white blood cells (leukocytes) and has been found in a wide variety of body cells. Interleukin 5 or IL-5 is produced by T helper-2 cells and mast cells. It helps to stimulate B cell growth and increase immunoglobulin secretion and is considered a key mediator in eosinophil activation. Interleukin 5 (IL-5) has long been associated with several allergic diseases, including allergic rhinitis and asthma. Growth in the number of circulating, airway tissue, and induced sputum eosinophils have been observed in patients with these diseases. IL-5 also had something with the terminally differentiated granulocyte eosinophils. IL-5 was originally found as an eosinophil colony-stimulating factor. It has been proved to be a major regulator of eosinophil accumulation in tissues and can modulate eosinophil behavior at every stage from maturation to survival.
别名 TRF, 白介素, EDF, interleukin 5, IL-5, 白细胞介素
分子量 Approxiamtely 13.1 kDa

存储

Lyophilized powder: -20~-80°C for 1 year

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TargetMol Library Books参考文献

1. Milburn MV,et al.(1993) A novel dimer configuration revealed by the crystal structure at 2.4 A resolution of human interleukin-5. Nature. 363(6425): 172-176. 2. Lee JS,et al.(1989) The IL-4 and IL-5 genes are closely linked and are part of a cytokine gene cluster on mouse chromosome 11. Somat Cell Mol Genet. 15(2): 143-152. 3. Woodcock JM,et al.(1994) Three residues in the common beta chain of the human GM-CSF, IL-3 and IL-5 receptors are essential for GM-CSF and IL-5 but not IL-3 high affinity binding and interact with Glu21 of GM-CSF. EMBO J. 13 (21): 5176-85.

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母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。

体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。

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Keywords

IL-5 Protein, Human, Recombinant TRF IL 5 白介素 IL5 EDF interleukin 5 IL-5 白细胞介素 Inhibitor inhibitor inhibit

 

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