规格

价格

库存

数量

5 mg

¥ 6,990

待询

10 mg

¥ 11,900

待询

生物活性

产品描述

Ascr#7 is a small-molecule glycolipid pheromone secreted by Caenorhabditis elegans, belonging to the ascaroside family. These compounds are often referred to as "dauer pheromones" and serve as critical chemical signals regulating development, social behavior, and stress responses in nematodes. The expression of Ascr#7 is strongly dependent on diet and developmental stage. Its primary biological function is to induce the formation of long-lived and highly stress-resistant dauer larvae. This mechanism allows nematodes to arrest normal development and enter a specialized diapause state for survival during adverse environmental conditions such as food scarcity or high population density.

体外活性

Ascr#7 作为线虫中强效的发育调节剂，通过感觉 GPCR 触发其向耐受期发育通路的转变。其生物合成和分泌受营养状况和群体密度的动态调节，是反映环境质量的生物指标 [1]。

化学信息

分子量	274.31
分子式	C₁₃H₂₂O₆
CAS No.	1139837-37-8
Smiles	O([C@@H](CC/C=C/C(O)=O)C)[C@H]1[C@H](O)C[C@@H](O)[C@H](C)O1

储存&溶解度

存储

keep away from direct sunlight | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

H2O: 80.00 mg/mL (291.64 mM), Sonication is recommended.

DMSO: 160.00 mg/mL (583.28 mM), Sonication is recommended.

溶液配制表

H2O/DMSO

	1mg	5mg	10mg	50mg
1 mM	3.6455 mL	18.2276 mL	36.4551 mL	182.2755 mL
5 mM	0.7291 mL	3.6455 mL	7.2910 mL	36.4551 mL
10 mM	0.3646 mL	1.8228 mL	3.6455 mL	18.2276 mL
20 mM	0.1823 mL	0.9114 mL	1.8228 mL	9.1138 mL
50 mM	0.0729 mL	0.3646 mL	0.7291 mL	3.6455 mL
100 mM	0.0365 mL	0.1823 mL	0.3646 mL	1.8228 mL

Ascr#7

Ascr#7

产品介绍

计算器

体内实验配液计算器

剂量转换

引用文献

关键词