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Anti-Zona pellucida glycoprotein 4 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Zona pellucida glycoprotein 4。Anti-Zona pellucida glycoprotein 4 Polyclonal Antibody 可用于 WB。
Anti-Zona pellucida glycoprotein 4 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Zona pellucida glycoprotein 4。Anti-Zona pellucida glycoprotein 4 Polyclonal Antibody 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,165 | 5日内发货 | |
| 100 μL | ¥ 1,970 | 5日内发货 | |
| 200 μL | ¥ 2,785 | 5日内发货 |
| 产品描述 | Anti-Zona pellucida glycoprotein 4 Polyclonal Antibody is a Rabbit antibody targeting Zona pellucida glycoprotein 4. Anti-Zona pellucida glycoprotein 4 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| 反应种属 | Mouse (predicted:Human,Rat,Horse) |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Secreted > extracellular space > extracellular matrix and Cell membrane. |
| 组织特异性 | Oocytes. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. The nascent protein contains a N-terminal signal peptide sequence, a conserved ZP domain, a consensus furin cleavage site, and a C-terminal transmembrane domain. It is hypothesized that furin cleavage results in release of the mature protein from the plasma membrane for subsequent incorporation into the zona pellucida matrix. However, the requirement for furin cleavage in this process remains controversial based on mouse studies. Previously, this gene has been referred to as ZP1 or ZPB and thought to have similar functions as mouse Zp1. However, a human gene with higher similarity and chromosomal synteny to mouse Zp1 has been assigned the symbol ZP1 and this gene has been assigned the symbol ZP4. [provided by RefSeq, Jul 2008] |
| 免疫原 | KLH conjugated synthetic peptide: human ZP4 |
| 抗原种属 | Human |
| 基因名称 | ZP4 |
| 基因ID | |
| 蛋白名称 | Zona pellucida sperm-binding protein 4 |
| Uniprot ID | |
| 功能 | The mammalian zona pellucida, which mediates species-specific sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy, is composed of three to four glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP4 may act as a sperm receptor. |
| 分子量 | Theoretical: 57 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |