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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Wnt16 Polyclonal Antibody

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货号 TMAB-14186

Anti-Wnt16 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Wnt16。Anti-Wnt16 Polyclonal Antibody 可用于 WB。

Anti-Wnt16 Polyclonal Antibody

Anti-Wnt16 Polyclonal Antibody

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货号 TMAB-14186

Anti-Wnt16 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Wnt16。Anti-Wnt16 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-Wnt16 Polyclonal Antibody is a Rabbit antibody targeting Wnt16. Anti-Wnt16 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Pig,Cow,Rabbit)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Secreted.extracellular space, extracellular matrix.
组织特异性Isoform Wnt-16b is expressed in peripheral lymphoid organs such as spleen, appendix, and lymph nodes, in kidney but not in bone marrow. Isoform Wnt-16a is expressed at significant levels only in the pancreas.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The Wnt genes encode a family of secreted extracellular signaling glycoproteins, which function in a variety of important developmental processes such as regulation of cell growth and differentiation. Wnt proteins also play roles in carcinogenesis. Wnt-14, rather than Wnt-15, is preferentially expressed in various types of human cancer. Wnt-15 is expressed in fetal and adult kidney and is most homologous to Wnt-14. Wnt-16, another member in the Wnt family, has two mRNA isoforms, Wnt-16a and Wnt-16b. These isoforms differ in the composition of their 5'UTR and first exon, which results in differential expression. Wnt-16a is expressed only in pancreas, whereas Wnt-16b is highly expressed in adult kidney, placenta, brain, heart and spleen, but not in bone marrow. However, Wnt-16 transcripts are present in bone marrow and cell lines derived from pre-B acute lymphoblastoid leukemia patients carrying the E2A-Pbx1 hybrid gene. Thus, Wnt-16 is a downstream target of E2A-Pbx1, and the Wnt-16-mediated autocrine growth mechanism may contribute to the development of t(1;19) pre-B acute lymphoblastoid leukemias.
抗原信息
免疫原
KLH conjugated synthetic peptide: human Wnt16
抗原种属
Human
基因名称
WNT16
基因ID
51384
蛋白名称
Protein Wnt-16
Uniprot ID
Q9UBV4
功能
Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters
化学信息
分子量Theoretical: 37 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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