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Anti-TNF alpha Antibody (8E395)

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货号 TMAB-13621

Anti-TNF alpha Antibody (8E395) 是一种 Mouse 抗体，靶向 TNF alpha。Anti-TNF alpha Antibody (8E395) 可用于 ICC/IF,FCM。

Anti-TNF alpha Antibody (8E395)

Anti-TNF alpha Antibody (8E395)

一键复制产品信息
Rating icon 还可以
货号 TMAB-13621

Anti-TNF alpha Antibody (8E395) 是一种 Mouse 抗体，靶向 TNF alpha。Anti-TNF alpha Antibody (8E395) 可用于 ICC/IF,FCM。

规格价格库存数量
200 μg
¥ 5,585
5日内发货
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-TNF alpha Antibody (8E395) is a Mouse antibody targeting TNF alpha. Anti-TNF alpha Antibody (8E395) can be used in ICC/IF,FCM.
Ig Type
IgG
克隆号
8E395
反应种属
Human
应用ICC/IFFCM
推荐剂量
ICC/IF: 1:100-500; FCM: 1μg/Test
抗体种类
Monoclonal
宿主来源Mouse
亚细胞定位Cell membrane; Single-pass type II membrane protein. Tumor necrosis factor, membrane form: Membrane; Single-pass type II membrane protein. Tumor necrosis factor, soluble form: Secreted. C-domain 1: Secreted. C-domain 2: Secreted.
构建方式Hybridoma Monoclonal Antibody
纯化方式Protein G purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, psoriasis, rheumatoid arthritis ankylosing spondylitis, tuberculosis, autosomal dominant polycystic kidney disease, and cancer. Mutations in this gene affect susceptibility to cerebral malaria, septic shock, and Alzheimer disease. Knockout studies in mice also suggested the neuroprotective function of this cytokine. [provided by RefSeq, Aug 2020]
抗原信息
免疫原
Recombinant Protein: human TNF alpha protein
抗原种属
Human
基因名称
TNF
基因ID
7124
蛋白名称
Tumor necrosis factor
Uniprot ID
P01375
功能
Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation.
The TNF intracellular domain (ICD) form induces IL12 production in dendritic cells.
化学信息
分子量Theoretical: 17/26 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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