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Anti-SUR1 Polyclonal Antibody

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货号 TMAB-13279

Anti-SUR1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 SUR1。Anti-SUR1 Polyclonal Antibody 可用于 WB。

Anti-SUR1 Polyclonal Antibody

Anti-SUR1 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-13279

Anti-SUR1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 SUR1。Anti-SUR1 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍


生物活性
产品描述
Anti-SUR1 Polyclonal Antibody is a Rabbit antibody targeting SUR1. Anti-SUR1 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human,Mouse,Rat (predicted:Cow,Horse,Rabbit)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Membrane; Multi-pass membrane protein.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景SUR1 is a member of ATP binding cassette super family. SUR receptor confers the sensitivity of Kir6.2 to ATP/ADP sensitivity and to pharmacological agents such as sulfonylurea and diazoxide that close or open the KATP channels. The persistent heyperinsulinimic hypoglycemia in infancy (PHHI) is familial disorder due to defect in negative feed back in response to low glucose levels. SUR1 was mapped on chromosome 11p14-15.1, the same location where the gene for PHHI is located. It has been shown that the expression of Kir6.2 and SUR1 are regulated by glucose levels and the actives of glucogon like peptide receptor 1. Abnormal insulin secretion in PHHI appears to be caused by mutations in the SUR gene.
抗原信息
免疫原
KLH conjugated synthetic peptide: human SUR1
抗原种属
Human
基因名称
ABCC8
基因ID
蛋白名称
ATP-binding cassette sub-family C member 8
Uniprot ID
化学信息
分子量Theoretical: 175 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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