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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-SPO11 Polyclonal Antibody

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货号 TMAB-13128

Anti-SPO11 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 SPO11。Anti-SPO11 Polyclonal Antibody 可用于 WB。

Anti-SPO11 Polyclonal Antibody

Anti-SPO11 Polyclonal Antibody

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货号 TMAB-13128

Anti-SPO11 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 SPO11。Anti-SPO11 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-SPO11 Polyclonal Antibody is a Rabbit antibody targeting SPO11. Anti-SPO11 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human,Mouse,Rat (predicted:Dog,Pig,Horse)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nuclear
组织特异性Highly expressed in testis.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Spo11 is a type II topoisomerase that is thought to generate the chromosome breaks that initiate meiotic recombination. The Spo11 protein initiates meiotic recombination by generating DNA double-strand breaks (DSBs) and is required for meiotic synapsis in S. cerevisiae. The DSBs are located mostly in promoter regions, where the chromatin is in an open configuration, and cluster in domains along the chromosome. Expression of the Spo11 is detected mainly in the testis, in agreement with its predicted function in the initiation of meiotic recombination. Disruption of Spo11 leads to severe gonadal abnormalities from defective meiosis and results in infertility.
抗原信息
免疫原
KLH conjugated synthetic peptide: human SPO11
抗原种属
Human
基因名称
SPO11
基因ID
23626
蛋白名称
Meiotic recombination protein SPO11
Uniprot ID
Q9Y5K1
功能
Required for meiotic recombination. Mediates DNA cleavage that forms the double-strand breaks (DSB) that initiate meiotic recombination (By similarity). Essential for the phosphorylation of SMC3, HORMAD1 and HORMAD2 (By similarity).
化学信息
分子量Theoretical: 45 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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