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Anti-PTPN11 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 PTPN11。Anti-PTPN11 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF,FCM。
Anti-PTPN11 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 PTPN11。Anti-PTPN11 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,165 | 5日内发货 | |
| 100 μL | ¥ 1,965 | 5日内发货 | |
| 200 μL | ¥ 2,795 | 5日内发货 |
| 产品描述 | Anti-PTPN11 Polyclonal Antibody is a Rabbit antibody targeting PTPN11. Anti-PTPN11 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF,FCM. |
| Ig Type | IgG |
| 反应种属 | Human,Mouse (predicted:Rat,Chicken,Pig,Cow,Horse,Sheep) |
| 应用 | IHC-PIHC-FrIFFCM |
| 推荐剂量 | IHC-P: 1:100-500; IHC-Fr: 1:400-800; IF: 1:100-500; FCM: 1μg/Test |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cytoplasm. |
| 组织特异性 | Widely expressed, with highest levels in heart, brain, and skeletal muscle. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | The steady state of protein tyrosyl phosphorylation in cells is regulated by the opposing action of tyrosine kinases and protein tyrosine phosphatases (PTPs). Several groups have independently identified a non transmembrane PTP, designated SHPTP1 (also known as PTP1C, HCP and SHP), which is primarily expressed in hematopoietic cells and characterized by the presence of two SH2 domains N terminal to the PTP domain. A second and much more widely expressed PTP with SH2 domains, SHPTP2 (also designated PTP1D and Syp), has been identified. SHP2 is a protein tyrosine phosphatase that is widely expressed and plays a regulatory role in various cell |
| 免疫原 | KLH conjugated synthetic peptide: human PTPN11 |
| 抗原种属 | Human |
| 基因名称 | PTPN11 |
| 基因ID | |
| 蛋白名称 | Tyrosine-protein phosphatase non-receptor type 11 |
| Uniprot ID | |
| 功能 | Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Dephosphorylates ROCK2 at Tyr-722 resulting in stimulatation of its RhoA binding activity. |
| 分子量 | Theoretical: 68 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |