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Anti-IL-17RA Antibody-FITC (7E127)
还可以产品编号 TMAY-01300F
别名 interleukin 17 receptor A, IL-17RA, IL17R, hIL-17R, CDw217, CD217, CANDF5
Anti-IL-17RA Antibody-FITC (7E127) 是一种 FITC-conjugated Mouse 抗体，靶向 IL-17RA。Anti-IL-17RA Antibody-FITC (7E127) 可用于 FCM。
Anti-IL-17RA Antibody-FITC (7E127)
Anti-IL-17RA Antibody-FITC (7E127)
还可以产品编号 TMAY-01300F 别名 interleukin 17 receptor A, IL-17RA, IL17R, hIL-17R, CDw217, CD217, CANDF5
Anti-IL-17RA Antibody-FITC (7E127) 是一种 FITC-conjugated Mouse 抗体，靶向 IL-17RA。Anti-IL-17RA Antibody-FITC (7E127) 可用于 FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 T | ¥ 880 | 5日内发货 | |
| 100 T | ¥ 2,780 | 5日内发货 |
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抗原信息
| 产品描述 | Anti-IL-17RA Antibody-FITC (7E127) is a FITC-conjugated Mouse antibody targeting IL-17RA. Anti-IL-17RA Antibody-FITC (7E127) can be used in FCM. |
| 别名 | interleukin 17 receptor A, IL-17RA, IL17R, hIL-17R, CDw217, CD217, CANDF5 |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 7E127 |
| 交叉反应 | Human |
| 验证活性 | Flow cytometric analysis of Human IL17RA(CD217) expression on human whole blood granulocytes. Cells were stained with FITC-conjugated anti-Human IL17RA(CD217). The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable granulocytes. |
| 应用 | FCM |
| 推荐剂量 | 5 μl/Test, 0.1 mg/ml |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human IL17RA/IL-17RA/CD217 (rh IL17RA/IL-17RA/CD217; TMPY-01371; NP_055154.3; Met1-Trp320) and conjugated with FITC under optimum conditions, the unreacted FITC was removed. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| 研究背景 | Interleukin-17 receptor (IL-17R), also known as Interleukin-17 receptor A (IL-17RA) and CD217 antigen (CD217), is a cytokine receptor that binds interleukin 17. IL-17R/IL-17RA (CD217) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. IL-17R/IL-17RA (CD217) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor IL-17RA play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Defects in IL-17R/IL-17RA (CD217) are the cause of familial candidiasis type 5 (CANDF5). CANDF5 is a rare disorder with altered immune responses and impaired clearance of fungal infections, selective against Candida. It is characterized by persistent and/or recurrent infections of the skin, nails, and mucous membranes caused by organisms of the genus Candida, mainly Candida albicans. |
| 偶联 | FITC |
| 其他可选修饰符 | Unconjugated/APC/PE |
| 可提供抗体种类 | 4 |
| 免疫原 | Recombinant Human IL17RA/IL-17RA/CD217 Protein (TMPY-01371) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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