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Anti-EDARADD Polyclonal Antibody

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货号 TMAB-05435

Anti-EDARADD Polyclonal Antibody 是一种 Rabbit 抗体,靶向 EDARADD。Anti-EDARADD Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-EDARADD Polyclonal Antibody

Anti-EDARADD Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-05435

Anti-EDARADD Polyclonal Antibody 是一种 Rabbit 抗体,靶向 EDARADD。Anti-EDARADD Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍


生物活性
产品描述
Anti-EDARADD Polyclonal Antibody is a Rabbit antibody targeting EDARADD. Anti-EDARADD Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human,Rat (predicted:Mouse,Chicken,Dog,Pig,Cow,Horse,Sheep)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm.
组织特异性Detected in adult pancreas, placenta and fetal skin, and at lower levels in lung, thymus, prostate and testis.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene was identified by its association with ectodermal dysplasia, a genetic disorder characterized by defective development of hair, teeth, and eccrine sweat glands. The protein encoded by this gene is a death domain-containing protein, and is found to interact with EDAR, a death domain receptor known to be required for the development of hair, teeth and other ectodermal derivatives. This protein and EDAR are coexpressed in epithelial cells during the formation of hair follicles and teeth. Through its interaction with EDAR, this protein acts as an adaptor, and links the receptor to downstream signaling pathways. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
抗原信息
免疫原
KLH conjugated synthetic peptide: human EDARADD
抗原种属
Human
基因名称
EDARADD
基因ID
蛋白名称
Ectodysplasin-A receptor-associated adapter protein
Uniprot ID
功能
Adapter protein that interacts with EDAR DEATH domain and couples the receptor to EDA signaling pathway during morphogenesis of ectodermal organs. Mediates the activation of NF-kappa-B.
化学信息
分子量Theoretical: 25 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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