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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-E cadherin Antibody (3C746)

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货号 TMAB-05378

Anti-E cadherin Antibody (3C746) 是一种 Mouse 抗体，靶向 E cadherin。Anti-E cadherin Antibody (3C746) 可用于 IHC-P,IHC-Fr,IF。

Anti-E cadherin Antibody (3C746)

Anti-E cadherin Antibody (3C746)

一键复制产品信息
Rating icon 还可以
货号 TMAB-05378

Anti-E cadherin Antibody (3C746) 是一种 Mouse 抗体，靶向 E cadherin。Anti-E cadherin Antibody (3C746) 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,975
5日内发货
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产品介绍

生物活性
产品描述
Anti-E cadherin Antibody (3C746) is a Mouse antibody targeting E cadherin. Anti-E cadherin Antibody (3C746) can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
克隆号
3C746
反应种属
Human,Mouse,Rat (predicted:Monkey)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:500-2000; IHC-Fr: 1:500-2000; IF: 1:500-2000
抗体种类
Monoclonal
宿主来源Mouse
亚细胞定位Cell junction. Cell membrane; Single-pass type I membrane protein.
组织特异性Non-neural epithelial tissues.
构建方式Hybridoma Monoclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function of this gene is thought to contribute to cancer progression by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. This gene is present in a gene cluster with other members of the cadherin family on chromosome 16. [provided by RefSeq, Nov 2015]
抗原信息
免疫原
Recombinant Protein: human CADH1
抗原种属
Human
基因名称
CDH1
基因ID
999
蛋白名称
Cadherin-1
Uniprot ID
P12830
功能
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7.
E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production.
化学信息
分子量Theoretical: 97 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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