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Anti-DKK2 Antibody (3L558)

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货号 TMAB-05177

Anti-DKK2 Antibody (3L558) 是一种 Mouse 抗体,靶向 DKK2。Anti-DKK2 Antibody (3L558) 可用于 WB。

Anti-DKK2 Antibody (3L558)

Anti-DKK2 Antibody (3L558)

一键复制产品信息
Rating icon 还可以
货号 TMAB-05177

Anti-DKK2 Antibody (3L558) 是一种 Mouse 抗体,靶向 DKK2。Anti-DKK2 Antibody (3L558) 可用于 WB。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,965
5日内发货
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产品介绍


生物活性
产品描述
Anti-DKK2 Antibody (3L558) is a Mouse antibody targeting DKK2. Anti-DKK2 Antibody (3L558) can be used in WB.
Ig Type
IgG1, k
克隆号
3L558
反应种属
Human,Mouse
应用WB
推荐剂量
WB: 1:500-1000
抗体种类
Monoclonal
宿主来源Mouse
亚细胞定位Secreted.
组织特异性Expressed in heart, brain, skeletal muscle and lung.
构建方式Hybridoma Monoclonal Antibody
纯化方式Protein G purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. It can act as either an agonist or antagonist of Wnt/beta-catenin signaling, depending on the cellular context and the presence of the co-factor kremen 2. Activity of this protein is also modulated by binding to the Wnt co-receptor LDL-receptor related protein 6 (LRP6). [provided by RefSeq, Jul 2008]
抗原信息
免疫原
Recombinant Protein: human DKK2
抗原种属
Human
基因名称
DKK2
基因ID
蛋白名称
Dickkopf-related protein 2
Uniprot ID
功能
Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.
化学信息
分子量Theoretical: 25 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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