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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-CYP24A1 Polyclonal Antibody

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货号 TMAB-04875

Anti-CYP24A1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CYP24A1。Anti-CYP24A1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,ICC/IF,IF。

Anti-CYP24A1 Polyclonal Antibody

Anti-CYP24A1 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-04875

Anti-CYP24A1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CYP24A1。Anti-CYP24A1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,ICC/IF,IF。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-CYP24A1 Polyclonal Antibody is a Rabbit antibody targeting CYP24A1. Anti-CYP24A1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,ICC/IF,IF.
Ig Type
IgG
反应种属
Human,Mouse,Rat (predicted:Chicken,Dog,Pig,Cow,Horse,Rabbit)
应用IHC-PIHC-FrICC/IFIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Mitochondrion.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景CYP24A1 (cytochrome P450, family 24, subfamily A, polypeptide 1) is a member of the cytochrome P450 superfamily. It is a mitochondrial enzyme responsible for inactivating vitamin D3 metabolites through the C-24 oxidation pathway. In regulating the level of vitamin D3, CYP24A1 plays a role in calcium homeostasis and the vitamin D endocrine system. CYP24A1 also has a role in maintaining calcium homeostasis. It catalyzes the NADPH-dependent 24-hydroxylation of 25-hydroxyvitamin D(3) in the presence of adrenodoxin and NADPH-adrenodoxin reductase.
抗原信息
免疫原
KLH conjugated synthetic peptide: human CYP24A1
抗原种属
Human
基因名称
CYP24A1
基因ID
1591
蛋白名称
1, 25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial
Uniprot ID
Q07973
功能
Has a role in maintaining calcium homeostasis. Catalyzes the NADPH-dependent 24-hydroxylation of calcidiol (25-hydroxyvitamin D(3)) and calcitriol (1-alpha,25-dihydroxyvitamin D(3)). The enzyme can perform up to 6 rounds of hydroxylation of calcitriol leading to calcitroic acid. It also shows 23-hydroxylating activity leading to 1-alpha,25-dihydroxyvitamin D(3)-26,23-lactone as end product.
化学信息
分子量Theoretical: 55 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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