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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-ADRA1A Polyclonal Antibody

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货号 TMAB-02354

Anti-ADRA1A Polyclonal Antibody 是一种 Rabbit 抗体，靶向 ADRA1A。Anti-ADRA1A Polyclonal Antibody 可用于 WB。

Anti-ADRA1A Polyclonal Antibody

Anti-ADRA1A Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-02354

Anti-ADRA1A Polyclonal Antibody 是一种 Rabbit 抗体，靶向 ADRA1A。Anti-ADRA1A Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-ADRA1A Polyclonal Antibody is a Rabbit antibody targeting ADRA1A. Anti-ADRA1A Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Note=Location at the nuclear membrane facilitates heterooligomerization and regulates ERK-mediated signaling in cardiac myocytes. Colocalizes with GNAQ, PLCB1 as well as LAP2 at the nuclear membrane of cardiac myocytes.
组织特异性Expressed in heart, brain, liver and prostate, but not in kidney, lung, adrenal, aorta and pituitary. Within the prostate, expressed in the apex, base, periurethral and lateral lobe. Isoform 4 is the most abundant isoform expressed in the prostate with high levels also detected in liver and heart.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Lyophilized or Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1A-adrenergic receptor. Alternative splicing of this gene generates four transcript variants, which encode four different isoforms with distinct C-termini but having similar ligand binding properties. [provided by RefSeq, Jul 2008].
抗原信息
免疫原
KLH conjugated synthetic peptide: human ADRA1A
抗原种属
Human
基因名称
ADRA1A
基因ID
148
蛋白名称
alpha-1A adrenergic receptor
Uniprot ID
P35348
功能
This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine(PE)-stimulated ERK signaling in cardiac myocytes.
化学信息
分子量Theoretical: 51 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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