Cefozopran hydrochloride

规格	价格/CNY		数量
2 mg	￥ 272	5日内发货
5 mg	￥ 465	5日内发货
10 mg	￥ 600	5日内发货
25 mg	￥ 750	5日内发货
1 mL * 10 mM (in DMSO)	￥ 565	5日内发货

规格

价格/CNY

货期

数量

2 mg

￥ 272

5日内发货

5 mg

￥ 465

5日内发货

10 mg

￥ 600

5日内发货

25 mg

￥ 750

5日内发货

1 mL * 10 mM (in DMSO)

￥ 565

5日内发货

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

H2O: 30 mg/mL (54.35 mM), Sonication is recommended.

DMSO: 30 mg/mL (54.35 mM), Sonication is recommended.

产品描述	Cefozopran hydrochloride (SCE-2787 hydrochloride) is a fourth-generation cephalosporin. is a cell wall biosynthesis inhibitor with a broad spectrum of activity against Gram-positive and Gram-negative bacteria.
体外活性	Cefozopran hydrochloride (SCE-2787 hydrochloride), a fourth-generation cephalosporin, exhibits substantial activity against a range of bacteria. Cefozopran hydrochloride is effective against gram-positive organisms, including methicillin-susceptible staphylococci, enterococci, and viridans group streptococci. Additionally, Cefozopran hydrochloride demonstrates efficacy against gram-negative organisms such as Hemophilus influenza. Notably, Cefozopran hydrochloride displays comparatively good activity against enterococci and P. aeruginosa, which are typically resistant to other cephalosporins[2].
体内活性	In four-week-old ICR male mice, Cefozopran hydrochloride, administered subcutaneously at doses ranging from 5 to 80 mg/kg twice a day for 5 days, proves effective against acute respiratory tract infections caused by Kiebsiella pneumonia DT-S. In a model of chronic respiratory tract infection induced by K. pneumoniae 27, Cefozopran hydrochloride, at doses between 20 and 80 mg/kg administered subcutaneously twice a day for 7 days in five-week-old CBA/J female mice, exhibits effectiveness comparable to Ceftazidime[2].

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