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3-Iodothyronamine is derived from the deiodination and decarboxylation of endogenous thyroxine. It activates the G protein-coupled receptor known as trace amine-associated receptor 1 at nanomolar concentrations whereupon it rapidly influences thyroid hormone actions including body temperature, heart rate, and cardiac output. It has also been reported to function in controlling lipid and glucose utilization, hormonal secretion, and neuronal function, and has been considered for use in chemically-induced hibernation for medical purposes.
3-Iodothyronamine is derived from the deiodination and decarboxylation of endogenous thyroxine. It activates the G protein-coupled receptor known as trace amine-associated receptor 1 at nanomolar concentrations whereupon it rapidly influences thyroid hormone actions including body temperature, heart rate, and cardiac output. It has also been reported to function in controlling lipid and glucose utilization, hormonal secretion, and neuronal function, and has been considered for use in chemically-induced hibernation for medical purposes.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
500 μg | 待估 | 35日内发货 | |
1 mg | 待估 | 35日内发货 | |
5 mg | 待估 | 35日内发货 |
3-Iodothyronamine (hydrochloride) 相关产品
产品描述 | 3-Iodothyronamine is derived from the deiodination and decarboxylation of endogenous thyroxine. It activates the G protein-coupled receptor known as trace amine-associated receptor 1 at nanomolar concentrations whereupon it rapidly influences thyroid hormone actions including body temperature, heart rate, and cardiac output. It has also been reported to function in controlling lipid and glucose utilization, hormonal secretion, and neuronal function, and has been considered for use in chemically-induced hibernation for medical purposes. |
分子量 | 391.63 |
分子式 | C14H15ClINO2 |
CAS No. | 788824-64-6 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
溶解度信息 | Ethanol: 25 mg/mL (63.84 mM), Sonication is recommended. DMSO: 30 mg/mL (76.6 mM), Sonication is recommended. PBS (pH 7.2): 0.1 mg/mL (0.26 mM), Sonication is recommended. DMF: 50 mg/mL (127.67 mM), Sonication is recommended. |
以上为“体内实验配液计算器”的使用方法举例,并不是具体某个化合物的推荐配制方式,请根据您的实验动物和给药方式选择适当的溶解方案。
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