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PAFR

PAFR

The platelet-activating factor receptor is a G-protein coupled receptor which binds platelet-activating factor. The PAF receptor shows structural characteristics of the rhodopsin (MIM 180380) gene family and binds platelet-activating factor (PAF). PAF is a phospholipid (1-0-alkyl-2-acetyl-sn-glycero-3-phosphorylcholine) that has been implicated as a mediator in diverse pathologic processes, such as allergy, asthma, septic shock, arterial thrombosis, and inflammatory processes.[supplied by OMIM][7] Its pathogenetic role in chronic kidney failure has also been reported recently.
TargetMol
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Cat. No. Product Name CAS No. Purity Chemical Structure
T17178 Tulopafant
妥洛帕泛
116289-53-3 99.38%
TargetMol Chemical Structure Tulopafant
Tulopafant(RP 59227) 是一种有效的血小板活化因子 (PAF) 拮抗剂,可增加毛细血管通畅性并延长异体心脏移植的生存期。
T14007 PAF-AN-1
PAF拮抗剂1
115621-84-6 98.06%
TargetMol Chemical Structure PAF-AN-1
PAF-AN-1是一种新型有效的血小板激活因子受体 (PAF) 拮抗剂,参与研究过敏性死亡。
T3P2855 Chamigrenal
恰米醛
19912-84-6
TargetMol Chemical Structure Chamigrenal
β-Chamigrenal has anti-inflammatory activity, it has inhibitory effects on lipopolysaccharide-induced nitric oxide and prostaglandin E2 production in RAW 264.7 m...
TN4795 Piperenone
化合物 TN4795
57625-31-7 98%
TargetMol Chemical Structure Piperenone
Piperenone is an insect antifeeding substance. It has anti-platelet-activating factor(PAF) activities, is a PAF-acether antagonist.
TN4797 Piperolactam C
化合物 TN4797
116064-76-7 98%
TargetMol Chemical Structure Piperolactam C
Piperolactam C possesses anti-platelet aggregation activity in vitro. It can inhibit the growth of the fungi Cladosporium sphaerospermum and C. cladosporioides.
TN4796 Piperlotine D
化合物 TN4796
958296-13-4 98%
TargetMol Chemical Structure Piperlotine D
Piperlotine D shows potent antiplatelet aggregation activity.
TN4794 Pinusolidic acid
化合物 TN4794
40433-82-7 98%
TargetMol Chemical Structure Pinusolidic acid
Pinusolidic acid shows a potent inhibitory effect on platelet activating factor (PAF) binding to rabbit platelets (IC50 = 2.3 x 10(-5) M, 7.48 +/- 2.11 microgram...
TN3348 (+)-Acuminatin
化合物 TN3348
41744-39-2 98%
TargetMol Chemical Structure (+)-Acuminatin
(+)-Acuminatin exerts hepatoprotective activities, perhaps by serving as a potent antioxidant. (+)-trans-Acuminatin, and (+)-cis-acuminatin show weak activity ag...
TN2763 2-Hydroxy-3-methoxybenzoic acid glucose ester
化合物 TN2763
172377-87-6 98%
TargetMol Chemical Structure 2-Hydroxy-3-methoxybenzoic acid glucose ester
2-Hydroxy-3-methoxybenzoic acid glucose ester shows a potent antagonistic activity against platelet activating factor (PAF), it can prevent the mice from the PAF...
TN3153 6-Acetyl-2,2-dimethylchroman-4-one
化合物 TN3153
68799-41-7 98%
TargetMol Chemical Structure 6-Acetyl-2,2-dimethylchroman-4-one
6-Acetyl-2,2-dimethylchroman-4-one and vanillin show anti-platelet aggregation activity induced by arachidonic acid in vitro.
TN1654 Futoquinol
细叶青蒌藤醌醇
28178-92-9 98%
TargetMol Chemical Structure Futoquinol
Futoquinol is an anti-platelet activating factor principle from the stem part of Piper futokadsura (Piperaceae), the Chinese drug haifengteng.
TN3445 Aristolactam BIII
化合物 TN3445
53948-10-0 98%
TargetMol Chemical Structure Aristolactam BIII
Aristolactam BIII possesses anti-platelet aggregation activity in vitro, it also shows significant cytotoxic activity (IC50 values < 4 microg/mL) against P-388, ...
TN3723 Cryptomeridiol
化合物 TN3723
4666-84-6 98%
TargetMol Chemical Structure Cryptomeridiol
Cryptomeridiol is a potential skin-whitening agent, exhibits melanogenesis inhibitory activity on α-MSH-stimulated B16 melanoma cells. Cryptomeridiol has low act...
TL0014 Pinusolide
化合物 TL0014
31685-80-0 98%
TargetMol Chemical Structure Pinusolide
Pinusolide is a platelet activating factor ( PAF) antagonist, it may prove of therapeutic value in the treatment of hypotension, it has antileukemic potential, a...
TN3161 6-Deoxyjacareubin
6-脱氧巴西红厚壳素
16265-56-8 98%
TargetMol Chemical Structure 6-Deoxyjacareubin
6-Deoxyjacareubin 具有有效的抗氧化和抗真菌活性。 6-Deoxyjacareubin 抑制血小板活化因子 (PAF) 受体,IC50 为 29.0 microM,可用于天然 PAF 受体拮抗剂的研究。
TMA2418 1-Methoxyphaseollidin
化合物 TMA2418
65428-13-9 98%
TargetMol Chemical Structure 1-Methoxyphaseollidin
1-Methoxyphaseollidin exhibits anti-Helicobacter pylori activity against the CLAR and AMOX-resistant strain as well as four CLAR (AMOX)-sensitive strains. 1-Meth...
TN4600 Myrianthic acid
化合物 TN4600
89786-84-5 98%
TargetMol Chemical Structure Myrianthic acid
Myrianthic acid shows anticancer activity, it shows inhibitory activities on foam cell formation in human monocyte-derived macrophages induced by acetylated low-...
TN4821 Pregomisin
化合物 TN4821
66280-26-0 98%
TargetMol Chemical Structure Pregomisin
Pregomisin shows platelet-activating factor (PAF) antagonistic activity and the IC 50 value is 4.8x10(-5) M.
TN2087 Piperlotine C
化合物Piperlotine C
886989-88-4 98%
TargetMol Chemical Structure Piperlotine C
Piperlotine C shows potent antiplatelet aggregation activity.
TN3740 Cyclocommunol
化合物 TN3740
145643-96-5 98%
TargetMol Chemical Structure Cyclocommunol
Cyclocommunol exhibits cytotoxicity against hepatocellular carcinoma (SMMC-7721) and gastric carcinoma (BGC-823 and SGC-7901) cell lines. It also shows strong in...
Tulopafant
T17178
Tulopafant(RP 59227) 是一种有效的血小板活化因子 (PAF) 拮抗剂,可增加毛细血管通畅性并延长异体心脏移植的生存期。
PAF-AN-1
T14007
PAF-AN-1是一种新型有效的血小板激活因子受体 (PAF) 拮抗剂,参与研究过敏性死亡。
Chamigrenal
T3P2855
β-Chamigrenal has anti-inflammatory activity, it has inhibitory effects on lipopolysaccharide-induced nitric oxide and prostaglandin E2 production in RAW 264.7 m...
Piperenone
TN4795
Piperenone is an insect antifeeding substance. It has anti-platelet-activating factor(PAF) activities, is a PAF-acether antagonist.
Piperolactam C
TN4797
Piperolactam C possesses anti-platelet aggregation activity in vitro. It can inhibit the growth of the fungi Cladosporium sphaerospermum and C. cladosporioides.
Piperlotine D
TN4796
Piperlotine D shows potent antiplatelet aggregation activity.
Pinusolidic acid
TN4794
Pinusolidic acid shows a potent inhibitory effect on platelet activating factor (PAF) binding to rabbit platelets (IC50 = 2.3 x 10(-5) M, 7.48 +/- 2.11 microgram...
(+)-Acuminatin
TN3348
(+)-Acuminatin exerts hepatoprotective activities, perhaps by serving as a potent antioxidant. (+)-trans-Acuminatin, and (+)-cis-acuminatin show weak activity ag...
2-Hydroxy-3-methoxybenzoic acid glucose ester
TN2763
2-Hydroxy-3-methoxybenzoic acid glucose ester shows a potent antagonistic activity against platelet activating factor (PAF), it can prevent the mice from the PAF...
6-Acetyl-2,2-dimethylchroman-4-one
TN3153
6-Acetyl-2,2-dimethylchroman-4-one and vanillin show anti-platelet aggregation activity induced by arachidonic acid in vitro.
Futoquinol
TN1654
Futoquinol is an anti-platelet activating factor principle from the stem part of Piper futokadsura (Piperaceae), the Chinese drug haifengteng.
Aristolactam BIII
TN3445
Aristolactam BIII possesses anti-platelet aggregation activity in vitro, it also shows significant cytotoxic activity (IC50 values < 4 microg/mL) against P-388, ...
Cryptomeridiol
TN3723
Cryptomeridiol is a potential skin-whitening agent, exhibits melanogenesis inhibitory activity on α-MSH-stimulated B16 melanoma cells. Cryptomeridiol has low act...
Pinusolide
TL0014
Pinusolide is a platelet activating factor ( PAF) antagonist, it may prove of therapeutic value in the treatment of hypotension, it has antileukemic potential, a...
6-Deoxyjacareubin
TN3161
6-Deoxyjacareubin 具有有效的抗氧化和抗真菌活性。 6-Deoxyjacareubin 抑制血小板活化因子 (PAF) 受体,IC50 为 29.0 microM,可用于天然 PAF 受体拮抗剂的研究。
1-Methoxyphaseollidin
TMA2418
1-Methoxyphaseollidin exhibits anti-Helicobacter pylori activity against the CLAR and AMOX-resistant strain as well as four CLAR (AMOX)-sensitive strains. 1-Meth...
Myrianthic acid
TN4600
Myrianthic acid shows anticancer activity, it shows inhibitory activities on foam cell formation in human monocyte-derived macrophages induced by acetylated low-...
Pregomisin
TN4821
Pregomisin shows platelet-activating factor (PAF) antagonistic activity and the IC 50 value is 4.8x10(-5) M.
Piperlotine C
TN2087
Piperlotine C shows potent antiplatelet aggregation activity.
Cyclocommunol
TN3740
Cyclocommunol exhibits cytotoxicity against hepatocellular carcinoma (SMMC-7721) and gastric carcinoma (BGC-823 and SGC-7901) cell lines. It also shows strong in...
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