efflux activity

γ-Tocotrienol (Plastochromanol) 是一种维生素 E 的活性形式。

Silybin 是一种来自于Silybum 的黄酮类化合物，可抑制P-糖蛋白辅助的细胞外流，可抑制细胞色素P450酶，具有耐受性良好的优点，可用于肝中毒和慢性肝炎及肝硬化的辅助治疗，在化妆品应用上具有抗氧化和抗炎活性，还能够阻断MCT8转运蛋白。

Majoranaquinone对4种Staphylococcus菌株、1种Moraxella菌株和1种Enterococcus菌株显示出良好的抑菌作用。此外，Majoranaquinone在E.coli ATCC 25922菌株中表现出显著的外排泵抑制活性，并能有效抑制E.coli ATCC 25922和E.coli K-12 AG100的生物膜形成。

Boeravinone B (Standard) 是 Boeravinone B 的标准品。适用于定量分析、质量控制及生化实验等相关研究。Boeravinone B, a novel efflux pump inhibitor, apart from inhibiting the MdeA mediated efflux, also significantly inhibit the biofilm formation of S. aureus, boeravinone B may be used in combination with mupirocin for further development. Boeravinone B exhibits significant anti-inflammatory activity (56.6% at 50 mg/kg) when evaluated in an in vivo carrageenan-induced rat paw model.

Chrysosplenol D 属于甲氧基黄酮类化合物，可诱导 ERK1/2 介导的三阴性人乳腺癌细胞凋亡。它还显示出抗炎和中等抗锥虫活性。

Roemerine ((-)-Roemerine) 是一种来自塞内加尔番荔枝的卟啉生物碱，具有抗真菌和抗癌活性，通过抑制 Bmr 来防止小檗碱外排。Roemerine 以浓度依赖性方式增加细胞膜通透性，可用于研究真菌感染和前列腺癌。

Boeravinone B, a novel efflux pump inhibitor, apart from inhibiting the MdeA mediated efflux, also significantly inhibit the biofilm formation of S. aureus, boeravinone B may be used in combination with mupirocin for further development. Boeravinone B exh

Bonducellin has anti-inflammatory activities, it can significantly and dose-dependently inhibit the inflammatory mediators; nitric oxide (NO), and cytokines [tumor necrosis factor (TNF)-alpha and interleukin (IL)-12. Bonducellin shows weak antimalarial ac