bms-2

BMS-2 是 Met Flt-3 VEGFR2 酪氨酸激酶抑制剂。

BMS-202 (PD1-PDL1 inhibitor 2) 是一种非肽类 PD-1 PD-L 复合物抑制剂，其 IC50为 18 nM，KD 为 8 μM。它与 PD-L1 直接结合并阻断人类 PD-1 PD-L 的相互作用，具有抗肿瘤活性。

BMS-214662是一种选择性的 farnesyl transferase 抑制剂，具有抗肿瘤活性，可用于研究胰腺癌、头颈癌和肺癌。

BMS-212122 (UNII-0Z473OO6GB) 是一种有效的微粒体甘油三酯转移蛋白(MTP )抑制剂，在动物实验中显示出降血脂作用。BMS-212122 显著减少动脉粥样硬化斑块中的脂质含量和单核细胞衍生(CD68+)细胞。

BMS-265246 是一种有效的选择性 CDK1 2 抑制剂，对 CDK1 cyclin B 和 CDK2 cyclin E 的 IC50分别为6 nM 和9 nM。

BMS-279700 is a potent oral activity inhibitor that is part of a new family of aniline 5-azimidazolaquoxaline analogs and has excellent anti-inflammatory activity in vivo, as well as in vitro activity against p56LCK and T cell proliferation, blocking the

N-deacetylated BMS-202 是 PD-1 PD-L1 相互作用的抑制剂，具有潜在的抗癌活性，可用于研究癌症。

BMS-248360 is a potent and orally active dual antagonist of both angiotensin II receptor (AT1) and endothelin A (ETA) receptor. With Kis of 10 nM and 1.9 nM for hAT1 and hETA receptor, respectively. BMS-248360 shows hypertensive effects[1].

BMS-214662 mesylate 是一种高效且选择性的farnesyl transferase抑制剂，IC50值为1.35 nM，并且展现出抗肿瘤活性，适用于癌症研究。

BMS-242 is an effective inhibitor of PD-1/PD-L1 interaction.

BMS-250749 is a fluoroglycosylated fluoroindolocarbazole, it has antitumor activity.

BMS-281384 is a highly potent, phosphodiesterase 5 (PDE 5)-selective inhibitor.

BMS-210285 is a bio-active chemical.

BMS-229724 is a tightly bound inhibitor of cytoplasmic phospholipase A2 with anti-inflammatory activity.

BMS-243117 is an effective selective LCK inhibitor with good cell activity (IC(50)=1.1 microM) and inhibition of T cell proliferation, which has great potential for therapeutic immunosuppression and the treatment of diseases such as rheumatoid arthritis a

BMS-247243 is a novel cephalosporin inhibitor that is mainly active against Gram-positive bacteria and also against methicillin-resistant Staphylococcus.

BMS-262084 is a potent selective β-lactam trypsin inhibitor with therapeutic potential in the treatment of asthma.

BMS-284640 is a Na(+) H(+) exchange agent (NHE) inhibitor that has provided substantial protection in various animal models of myocardial ischemia (MI) and reperfusion in preclinical studies.

BMS-200 is a potent PD-1 PD-L1 interaction inhibitor with IC50 of 80 nM.

Ixabepilone (Azaepothilone B) 是一种可口服的微管抑制剂，能够与微管蛋白结合，促进微管蛋白的聚合和微管的稳定，使细胞停滞在 G2-M 期，诱导细胞凋亡。

Muraglitazar (BMS-298585) 是一种 PPAR α γ的双激动剂，用于治疗2型糖尿病及相关血脂异常。Muraglitazar 对人 PPARα (EC50 = 320 nM)和 PPARγ(EC50 = 110 nM)具有较强的体外活性。

Edonentan 是一种有效的内皮素A（ETA）受体拮抗剂，可用于研究心脏衰竭。

Entecavir monohydrate (BMS-200475) 是一种选择性HBV 抑制剂，在HepG2细胞中的EC50值为3.75 nM。

Gatifloxacin (CG5501) 是一种具有广谱抗菌活性的氟喹诺酮类抗生素。它可抑制大肠杆菌 DNA 解旋酶 (IC50=0.109 μg ml) 和细菌 II 型拓扑异构酶(IC50=13.8 μg ml)。在动物模型中，它有抗细菌性结膜炎作用。