Name: Damulin A
Brand: TargetMol
SKU: TN3758
Price: 3330 CNY
Availability: InStock
Rating: 5 (10 reviews)

规格

价格

库存

数量

10 mg

¥ 3,330

现货

产品介绍

生物活性

产品描述	Damulin A is an active dammarane-type saponin isolated from Gynostemma pentaphyllum and belongs to a group of structurally related compounds whose anticancer structure–activity relationships have been deeply explored. Comparative investigations reveal that double bonds positioned at C20(21) and C20(22) and hydroxyl modification at C-2 significantly contribute to cytotoxicity, as evidenced by proliferation inhibition in A549 cells. These findings confirm the importance of Damulin A within the broader context of Gynostemma-derived anticancer leads.
体外活性	Damulin A具有抗癌活性，对人非小细胞肺癌A549细胞表现出较强的细胞毒性 (IC50 = 59.2 μM) [1]。
别名	达木林 A

化学信息

分子量	783.01
分子式	C₄₂H₇₀O₁₃
CAS No.	1202868-74-3
Smiles	C[C@]12[C@@]([C@]3(C)[C@@](CC1)(C(C)(C)[C@@H](O[C@H]4[C@H](O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)[C@@H](O)[C@H](O)[C@@H](CO)O4)[C@H](O)C3)[H])(C[C@@H](O)[C@]6([C@@]2(C)CC[C@@H]6\C(=C\CC=C(C)C)\C)[H])[H]
密度	1.31 g/cm3 (Predicted)
颜色	White
物理性状	Solid

储存&溶解度

存储

keep away from moisture,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMSO: 40 mg/mL (51.08 mM), Sonication is recommeded.

溶液配制表

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.2771 mL	6.3856 mL	12.7712 mL	63.8561 mL
5 mM	0.2554 mL	1.2771 mL	2.5542 mL	12.7712 mL
10 mM	0.1277 mL	0.6386 mL	1.2771 mL	6.3856 mL
20 mM	0.0639 mL	0.3193 mL	0.6386 mL	3.1928 mL
50 mM	0.0255 mL	0.1277 mL	0.2554 mL	1.2771 mL

体内实验配液计算器