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Anti-AMH Antibody (5V998)

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产品编号 TMAY-02833
别名 MIS, MIF, anti-Mullerian hormone

Anti-AMH Antibody (5V998) 是一种 Mouse 抗体,靶向 AMH。Anti-AMH Antibody (5V998) 可用于 IHC-P。

Anti-AMH Antibody (5V998)

Anti-AMH Antibody (5V998)

Rating icon 还可以
产品编号 TMAY-02833 别名 MIS, MIF, anti-Mullerian hormone

Anti-AMH Antibody (5V998) 是一种 Mouse 抗体,靶向 AMH。Anti-AMH Antibody (5V998) 可用于 IHC-P。

规格价格库存数量
100 μL
¥ 1,684
5日内发货
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产品介绍

生物活性
产品描述
Anti-AMH Antibody (5V998) is a Mouse antibody targeting AMH. Anti-AMH Antibody (5V998) can be used in IHC-P.
别名MIS, MIF, anti-Mullerian hormone
Ig Type
Monoclonal Mouse IgG1
克隆号
5V998
交叉反应
Human
验证活性
Immunochemical staining of human AMH in human testis with mouse monoclonal antibody at 1:30 dilution, formalin-fixed paraffin embedded sections.
应用
IHC-P
推荐剂量
IHC-P: 1:20-1:50
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human AMH (rh AMH; TMPY-05176; NP_000470.2; Leu25-Arg560). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Anti-Mullerian hormone (AMH), a member of the TGF-beta superfamily, is produced by granulosa cells (GCs) of preantral and small antral follicles and plays a role in regulating the recruitment of primordial follicles and the FSH-dependent development of follicles. BMP15 up-regulates the transcription of AMH and that the inhibition of p38 MAPK decreases the BMP15-induced expression of AMH and SOX9, suggesting that BMP15 up-regulates the expression of AMH via the p38 MAPK signaling pathway, and this process involves the SOX9 transcription factor. AMH is widely used for assessing ovarian reserve, and it is particularly convenient, because it is thought to have minimal variability throughout the menstrual cycle. Fetal anti-Mullerian hormone (AMH) is responsible for normal male sexual differentiation, and circulating AMH is used as a marker of testicular tissue in newborns with disorders of sex development. Anti-Mullerian hormone (AMH) produced in the developing testis induces the regression of the Mullerian duct, which develops into the oviducts, uterus and upper vagina. As well as other hormone receptors, and a decreased ovarian cortex cell proliferation. These results help understand the inhibitory effects of AMH on follicular development.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Human AMH Protein (TMPY-05176)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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