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2-O-α-D-Glucopyranosyl-L-ascorbic Acid

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纯度: 99.73%

货号 T8172Cas号 129499-78-1

别名 抗坏血酸葡糖苷, ASCORBYL GLUCOSIDE, 2-O-α-D-吡喃葡萄糖基-L-抗坏血酸

2-O-α-D-Glucopyranosyl-L-ascorbic Acid (ASCORBYL GLUCOSIDE) 是一种抗坏血酸的葡萄糖苷衍生物,可以被酶水解成为抗坏血酸,能够表现出抗癌活性。

2-O-α-D-Glucopyranosyl-L-ascorbic Acid
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2-O-α-D-Glucopyranosyl-L-ascorbic Acid

一键复制产品信息
Rating icon 很棒

纯度: 99.73%

货号 T8172 别名 抗坏血酸葡糖苷, ASCORBYL GLUCOSIDE, 2-O-α-D-吡喃葡萄糖基-L-抗坏血酸Cas号 129499-78-1

2-O-α-D-Glucopyranosyl-L-ascorbic Acid (ASCORBYL GLUCOSIDE) 是一种抗坏血酸的葡萄糖苷衍生物,可以被酶水解成为抗坏血酸,能够表现出抗癌活性。

规格价格库存数量
10 mg
¥ 137
现货
25 mg
¥ 203
现货
50 mg
¥ 278
现货
100 mg
¥ 358
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500 mg
¥ 876
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1 g
¥ 1,290
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1 mL x 10 mM (in DMSO)
¥ 150
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产品介绍


2-O-α-D-Glucopyranosyl-L-ascorbic Acid AI Summary
2-O-α-D-Glucopyranosyl-L-ascorbic Acid exhibits significant antioxidant activity by scavenging hydroxy radicals and reducing inorganic phosphate levels using alpha-glycerophosphate as a substrate, as well as reducing hydroxy radical and acetaldehyde levels when using ethylene glycol as a substrate. The compound also demonstrates potent antioxidant properties by scavenging DPPH free radicals, with activity levels ranging from 1.5 to 2.7 moles of radicals scavenged per mol of antioxidant. Additionally, it was observed to consume 190.0 uM of radicals and form AA-2G-DPPH adducts at 200 uM concentration, with a retention time of 15.0 minutes for the AA-2G-DPPH product. Furthermore, 2-O-α-D-Glucopyranosyl-L-ascorbic Acid exhibits antiviral activity against Herpes simplex virus type 1 in human RD cells by inhibiting virus-induced cytopathic effects, indicating potential specificity towards the virus based on the selectivity ratio of maximum non-toxic concentration for human RD cells to the effective concentration for HSV1..
Note: Summary generated by AI. Data source: ChEMBL
生物活性
产品描述
2-O-α-D-Glucopyranosyl-L-ascorbic Acid (ASCORBYL GLUCOSIDE), a glucoside derivative of ascorbic acid, demonstrates anti-cancer activity following enzymatic hydrolysis to ascorbic acid.
别名抗坏血酸葡糖苷, ASCORBYL GLUCOSIDE, 2-O-α-D-吡喃葡萄糖基-L-抗坏血酸
化学信息
分子量338.26
分子式C12H18O11
CAS No.129499-78-1
SmilesOC[C@H](O)[C@H]1OC(=O)C(O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)=C1O
密度1.83 g/cm3 (Predicted)
储存&溶解度
存储keep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
溶解度信息
H2O: 33 mg/mL (97.56 mM), Sonication is recommended.
DMSO: 33 mg/mL (97.56 mM), Sonication is recommended.
溶液配制表
H2O/DMSO
1mg5mg10mg50mg
1 mM2.9563 mL14.7815 mL29.5631 mL147.8153 mL
5 mM0.5913 mL2.9563 mL5.9126 mL29.5631 mL
10 mM0.2956 mL1.4782 mL2.9563 mL14.7815 mL
20 mM0.1478 mL0.7391 mL1.4782 mL7.3908 mL
50 mM0.0591 mL0.2956 mL0.5913 mL2.9563 mL

计算器

  • 摩尔浓度 计算器
  • 稀释 计算器
  • 配液 计算器
  • 分子量 计算器

体内实验配液计算器

请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法:
TargetMol | Animal experiments 比如您的给药剂量是10 mg/kg,每只动物体重20g,给药体积100 μLTargetMol | Animal experiments 一共给药动物10只,您使用的配方为5%TargetMol | reagent DMSO + 30%PEG300 + 5%Tween 80 + 60%Saline/PBS/ddH2O, 那么您的工作液浓度为2mg/mL
母液配置方法: 2 mg 药物溶于 50 μLDMSOTargetMol | reagent ( 母液浓度为 40 mg/mL ), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:50μLDMSOTargetMol | reagent 母液,添加 300 μLPEG300TargetMol | reagent 混匀澄清,再加 50μLTween80, 混匀澄清,再加 600μLSaline/PBS/ddH2OTargetMol | reagent 混匀澄清

以上为“体内实验配液计算器”的使用方法举例,并不是具体某个化合物的推荐配制方式,请根据您的实验动物和给药方式选择适当的溶解方案。

方案所需的各类助溶剂如: DMSOPEG300 / PEG400Tween 80SBE-β-CD玉米油 等, 均可在TargetMol网站点击购买。
1 请输入动物实验的基本信息
mg/kg
g
μL
2 请输入动物体内配方组成,不同的产品配方组成不同,如有配方需求,可先联系我们提供正确的体内配方。
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

剂量转换

对于不同动物的给药剂量换算,您也可以参考 更多

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