Mycophenolate Mofetil is a non-competitive, selective, and reversible inhibitor of inosine monophosphate dehydrogenase I II (IC50: 39 nM and 27 nM, respectively).
Dihydrohomofolic acid is a substrate for dihydrofolate reductase that produces tetrahydro-homo folate which in turn suppresses thymidylate synthetase and then DNA synthesis.
Emofolin sodium is the sodium salt of a synthetic antimetabolite analogue of folate with antineoplastic activity,which competes for the folate binding site of the enzyme dihydrofolate reductase, resulting in inhibition of tetrahydrofolate synthesis, deple