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抑制剂 & 化合物

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天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T21632	Myoseverin	Others; Microtubule Associated	Cytoskeletal Signaling; Others
	Myoseverina 是多核肌管可逆分裂成单核片段的诱导剂，影响多种生长因子、免疫调节、细胞外基质重塑和应激反应基因的表达，与伤口愈合和组织再生相关通路的激活一致。
T15368L	Galantide acetate Galantide acetate(138579-66-5 Free base)	Neuropeptide Y Receptor	GPCR/G Protein; Neuroscience
	Galantide acetate 是一种特殊的甘丙肽受体 (galanin receptor) 拮抗剂，是一种由甘丙肽和 P 物质片段组成的肽段，在大鼠下丘脑可识别两类甘丙肽结合位点 (KD 分别小于 0.1 nM 和 ~6 nM)。Galantide 剂量依赖性 (IC50=1.0 nM) 拮抗甘丙肽介导的葡萄糖诱导的小鼠胰岛胰岛素分泌抑制。Galantide acetate 似乎与单一的 SP 受体群结合 (KD~40 nM)。
TP1573L	CLIP 86-100 acetate(648881-58-7 free base)	Others	Others
	CLIP 86-100 acetate(648881-58-7 free base) 这是称为 CLIP 的 II 类相关不变链肽的氨基酸 86 至 100 片段。主要组织相容性复合物 II 类分子显示外源蛋白的肽片段，以触发免疫系统的防御反应。在将外源肽插入结合槽之前，去除一个占位肽 CLIP。这是通过分子 DM 实现的，它被证明可以增加 CLIP 肽与 II 类的解离速率。
TP1036	Sphistin Synthetic Peptide Sphistin Synthetic Peptide(12-38,Fitc in N-Terminal-Fluorescently Labeled Peptide)
	Sphistin Synthetic Peptide is a truncated fragments of Sphistin Synthetic Peptide that shows potent antimicrobial activity.
T34483	Sadopine
	Sadopine is an excellent high affinity, high specific activity radioligand to label selectively the DHP receptor of L-type Ca2+ channels in tissue sections as well as in membrane fragments.
T17060	Tetramethylrhodamine-5-iodoacetamide 5-TMRIA	Others	Others
	Tetramethylrhodamine-5-iodoacetamide (5-TMRIA) is a thiol-selective reactive dye that is used to non-specifically label proteins via the cysteine residues and covalently label DNA fragments[1].
T33538	Mycobactin S
	Mycobactin S is made from metabolic products of the acid-resistant form of Mycobacterium phlei, a tuberculosis bacillus derived originally from the cold-blooded sea turtle. Importantly, it is not based on cell wall fragments or killed bacteria.
TP2291	signal transducer and activator of transcription 6 fragment	Others	Others
	The signal transducer and activator of transcription 6 fragments is a peptide with the sequence H2N-Ser-Tyr-Trp-Ser-Asp-Arg-Leu-Ile-Ile-OH, MW= 1152.3.
TP1249	Adrenocorticotropic Hormone (ACTH) (1-39), rat ACTH (1-39) (mouse, rat)
	Adrenocorticotropic Hormone (ACTH) (1-39), rat is a potent melanocortin 2 (MC2) receptor agonist.Peptide fragments of ACTH (1-39) were formed during in vitro incubation of the peptide with membrane preparations. ACTH (1-39) were isolated by high pressure
T31187	Dactylorhin B
	Dactylorhin B is an active compound isolated from Coeloglossum Viride. Dactylorhin B reduces the toxic effects of β -amyloid fragments (25-35) on neuron cells and isolated rat brain mitochondria, which play an important role in neurodegenerative diseases.
TP1303	β-Amyloid (1-40) β-Amyloid 1-40
	Amyloid β1-40 is one of the fragments generated after cleavage of the amyloid peptide precursor protein by β and γ secretases.
T26447	A 78773 A78773,A-78773
	A 78773 is a potent, selective, direct, and reversible 5-lipoxygenase inhibitor. It has activity in a variety of purified cells and in more complex biological systems such as whole blood, lung fragments, and tracheal tissues. A 78773 acts against inflamma
T75957	Sphistin Synthetic Peptide(12-38,Fitc in N-Terminal-Fluorescently Labeled Peptide)
	Sphistin Synthetic Peptide (12-38, Fitc in N-Terminal-Fluorescently Labeled Peptide) 是Sphistin 合成肽的截短片段，具有有效的抗微生物 (antimicrobial) 活性。
TP1231	β-Amyloid (29-40) Amyloid beta-protein(29-40),β-Amyloid 29-40
	β-Amyloid (29-40) is a fragment of Amyloid-β peptide.Alzheimer's beta amyloid peptide (29-40/42) C-terminal fragments have physical and chemical properties related to those of fusion peptides of viral proteins. The fusion of liposomes can be induced by th
TP1249L	Adrenocorticotropic Hormone (ACTH) (1-39), rat acetate(77465-10-2 Free base)
	Adrenocorticotropic Hormone (ACTH) (1-39), rat acetate(77465-10-2 Free base) 是一种有效的黑皮质素 2 (MC2) 受体激动剂。ACTH (1-39) 的肽片段是在体外孵育过程中形成的肽与膜制剂。
T74551	Avacincaptad pegol sodium
	Avacincaptad pegol (ARC1905) 是一种靶向补体因子5 (C5)的核酸适配体，抑制C5剪切为C5a 和C5b。Avacincaptad pegol 被用于研究与年龄相关的黄斑变性(AMD)。
TP1573	CLIP (86-100) CLIP 86-100
	CLIP (86-100) is amino acids 86 to 100 fragment of class II-associated invariant chain peptide called CLIP. The major histocompatibility complex class II molecule displays peptide fragments of foreign proteins to trigger a defensive reaction from the immune system. Before insertion of the foreign peptides into the binding groove, a place-holding peptide CLIP is removed. CLIP (86-100) is accomplished by the molecule DM, which is shown to increase the dissociation rate of a CLIP peptide from class...
T61723	SS-RJW100
	SS-RJW100 is an enantiomer of RJW100, known as a racemic agonist that targets two nuclear receptors: liver receptor homolog 1 (LRH-1) and steroidogenic factor 1 (SF-1). In vitro experiments reveal that SS-RJW100 promotes the recruitment of coregulator protein fragments and enhances the interaction with the transcriptional intermediary factor 2 (Tif2) coactivator specifically for LRH-1. Additionally, SS-RJW100 disrupts the allosteric activation networks of LRH-1, displaying suboptimal thermal sta...
T83689	Histatin 8 TFA Hst-8
	Histatin 8是一种唾液抗微生物肽，是histatin 3和histatin 5的蛋白水解片段。针对A. baumannii（包括对colistin敏感或耐药的菌株）在32 µg/ml浓度下显示活性。Histatin 8也对C. albicans和C. tropicalis显示活性（MICs分别为1和5 mg/ml）。
T37140	5'-O-DMT-rI
	5’-O-DMT-Ri can be used in the synthesis of oligoribonucleotides[1]. [1]. Kadokura M. Synthesis of 4-thiouridine, 6-thioinosine, and 6-thioguanosine 3’,5’-O-bisphosphates as donor molecules for RNA ligation and their application to the synthesis of photoactivatable TMG-capped U1 snRNA fragments. J Org Chem. 2000 Aug 25;65(17):5104-13.
T76366	CART (55-76), rat
	CART (55-76), rat 为一种神经肽，构成CART (55-102)的N端片段，属于鼠源性饱腹感因子，具有显著的抑食作用，并与瘦素及神经肽Y关系紧密。此外，CART (55-76), rat 还能诱发与焦虑和压力相关的行为。
T82400	Ficain Ficin
	Ficain是从Ficus hispidaL.和无花果(Ficus carica)的乳胶中分离的一种蛋白酶混合酶提取物。该酶在果实成熟过程中各具特异性，比例各异。Ficain用途广泛，应用于蛋白质水解、食品加工、生物活性肽生产及抗体片段制备等领域。
TD0002L	CelRed nucleic acid gel stain 10,000× concentrate in DMSO
	1) Non-toxicity: The unique oiliness and high molecular weight characteristics of CelRed prevent it from penetrating cell membranes into cells. Ames test results also show that the mutagenicity of CelRed dye is much less than that of EB. 2) High sensitivi
T37394	13(S)-HpOTrE
	13(S)-HpOTrE is a monohydroperoxy polyunsaturated fatty acid produced in soybeans by the action of soybean LO-2 on esterified α-linolenic acid.[1] Incubation of soybean seedling biomembranes with soybean LO-2 catalyzes the formation of both 9- and 13-HpOTrE in a molar ratio of 10:1.1 In plants, 13(S)-HpOTrE can be metabolized by the hydroperoxide lyase pathway producing aldehyde and oxoacid fragments, or by the hydroperoxide dehydratase pathway producing jasmonic acid.[2],[3],[4] Treatment of to...
T36380	GLP-1 (1-36) amide (human, rat) (trifluoroacetate salt)
	GLP-1 amide is a peptide hormone cleaved from proglucagon in the pancreas.1,2 Mice lacking the glucagon receptor (Gcgr-/-) have approximately nine-fold higher levels of total GLP-1 amide, including GLP-1 (1-36) amide and truncated GLP-1 (7-36) amide , in pancreatic tissue compared to wild-type mice.2References1. Schjoldager, B.T., Mortensen, P.E., Christiansen, J., et al. GLP-1 (glucagon-like peptide 1) and truncated GLP-1, fragments of human proglucagon, inhibit gastric acid secretion in humans...
TD0002	CelRed nucleic acid gel stain 10,000× concentrate in water
	1) Non-toxicity: The unique oiliness and high molecular weight characteristics of CelRed prevent it from penetrating cell membranes into cells, and Ames test results also show that the mutagenicity of CelRed dye is much less than EB. 2) High sensitivity:
T35814	Urocortin III (human) (trifluoroacetate salt)
	Urocortin III is a neuropeptide hormone and member of the corticotropin-releasing factor (CRF) family which includes mammalian CRF , urocortin , urocortin II , frog sauvagine, and piscine urotensin I.1 Human urocortin III shares 90, 40, 37, and 21% identity to mouse urocortin III , mouse urocortin II , human urocortin , and mouse urocortin, respectively. Urocortin III selectively binds to type 2 CRF receptors (Kis = 21.7, 13.5, and >100 nM for rat CRF2α, rat CRF2β, and human CRF1, respectively)....

化合物

Cat.No: T21632

Target: Others, Microtubule Associated

Galantide acetate

Cat.No: T15368L

Synonym: Galantide acetate(138579-66-5 Free base)

Target: Neuropeptide Y Receptor

CLIP 86-100 acetate(648881-58-7 free base)

Cat.No: TP1573L

Target: Others

Sphistin Synthetic Peptide

Cat.No: TP1036

Synonym: Sphistin Synthetic Peptide(12-38,Fitc in N-Terminal-Fluorescently Labeled Peptide)

Cat.No: T34483

Tetramethylrhodamine-5-iodoacetamide

Cat.No: T17060

Synonym: 5-TMRIA

Target: Others

Cat.No: T33538

signal transducer and activator of transcription 6 fragment

Cat.No: TP2291

Target: Others

Adrenocorticotropic Hormone (ACTH) (1-39), rat

Cat.No: TP1249

Synonym: ACTH (1-39) (mouse, rat)

Cat.No: T31187

β-Amyloid (1-40)

Cat.No: TP1303

Synonym: β-Amyloid 1-40

Cat.No: T26447

Synonym: A78773,A-78773

Sphistin Synthetic Peptide(12-38,Fitc in N-Terminal-Fluorescently Labeled Peptide)

Cat.No: T75957

β-Amyloid (29-40)

Cat.No: TP1231

Synonym: Amyloid beta-protein(29-40),β-Amyloid 29-40

Adrenocorticotropic Hormone (ACTH) (1-39), rat acetate(77465-10-2 Free base)

Cat.No: TP1249L

Avacincaptad pegol sodium

Cat.No: T74551

Cat.No: TP1573

Synonym: CLIP 86-100

Cat.No: T61723

Cat.No: T83689

Synonym: Hst-8

Cat.No: T37140

CART (55-76), rat

Cat.No: T76366

Cat.No: T82400

Synonym: Ficin

CelRed nucleic acid gel stain *10,000× concentrate in DMSO*

Cat.No: TD0002L

Cat.No: T37394

GLP-1 (1-36) amide (human, rat) (trifluoroacetate salt)

Cat.No: T36380

CelRed nucleic acid gel stain *10,000× concentrate in water*

Cat.No: TD0002

Urocortin III (human) (trifluoroacetate salt)

Cat.No: T35814

Cat. No.	Product Name	Target	Signaling Pathways
T5227	Tricaprin Tridecanoin,Glyceryl tridecanoate,Glycerol Tridecanoate,TG(10:0/10:0/10:0),Glycerol tricaprate,甘油三癸酸酯,三癸酸甘油酯	Others; Endogenous Metabolite	Metabolism; Others
	Tricaprin (Glycerol Tridecanoate) 是癸酸的一种口服具有活性前体 (DA precursor)，能够被水解为癸酸。它是中链甘油三酸酯 (MCT) 的主要成分，具有抗雄激素和抗高血糖特性。它能够用做食品，药品，化妆品中的添加剂。

天然产物

Cat.No: T5227

Synonym: Tridecanoin,Glyceryl tridecanoate,Glycerol Tridecanoate,TG(10:0/10:0/10:0),Glycerol tricaprate,甘油三癸酸酯,三癸酸甘油酯

Target: Others, Endogenous Metabolite

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