spp 2

NO2-SPP-sulfo-Me is a cleavable linker utilized in the synthesis of antibody-drug conjugates (ADC)[1].

NO2-SPP is a cleavable linker used in the synthesis of antibody-drug conjugates (ADC).

NO2-SPP-sulfo is a cleavable linker vital in ADC synthesis. NO2-SPP-sulfo joins cytotoxic drugs to antibodies, enabling precise delivery to cells or proteins. The cleavable nature ensures controlled drug release, optimizing ADC effectiveness.

Avosentan（Ro 67-0565; SPP-301） 是有效的内皮素受体（ETA）拮抗剂,对内皮素-1诱导的收缩有很强的抑制作用,可能对慢性肾脏疾病具有保护作用。[2]

Resorantel 是一种驱虫剂，用于研究牛和羊的寄生虫病，也被用于研究G. aegypticus。

Antileishmanial agent-2 是一种基于 3-Br-isoxazoline 的疟原虫抑制剂恶性疟原虫（D10 和 W2 菌株）和利什曼原虫属。 (L. infantum 和 L.tropica) 前鞭毛体，IC50 为 0.035、0.058、3.5 和 7.5 μM。

BAL30072 shows MIC90 values of 4 μg mL for MDR Acinetobacter spp. and 8 μg mL for MDR P. aeruginosa, respectively[1][2]. BAL-30072, a siderophore sulfactam, is a monocyclic beta-lactam antibiotic, with activity against multiresistant gram-negative bacilli

Beta-Zearalenol, a derivative of zearalenone (ZEA) capable of conjugating with glucuronic acid[2], is a mycotoxin produced by Fusarium spp. It induces apoptosis and oxidative stress in mammalian reproductive cells[1].

Piliformic acid is a fungal metabolite that has been found inN. pseudotrichiaand has diverse biological activities.1,2It is cytotoxic to BC-1 human breast cancer cells (IC50= 5 μg ml).2Piloformic acid is active againstL. braziliensisamastigotes (IC50= 78.5 μM). It is also active against the plant pathogenic fungiC. gloeosporioides(MIC = 292 μM).1 1.Elias, L.M., Fortkamp, D., Sartori, S.B., et al.The potential of compounds isolated from Xylaria spp. as antifungal agents against anthracnoseBraz. J. Microbiol.49(4)840-847(2018) 2.Cota, B.B., Tunes, L.G., Maia, D.N.B., et al.Leishmanicidal compounds of Nectria pseudotrichia, an endophytic fungus isolated from the plant Caesalpinia echinata (Brazilwood)Mem. Inst. Oswaldo Cruz113(2)102-110(2018)

Grosshemin (Grosshemine)是一种广泛来自多种植物（如Centaurea属）的天然倍半萜内酯，对人肿瘤细胞系（A549、SK-OV-3、SK-MEL-2、HCT15）中抑制细胞增殖，具有抗癌潜力。

Omiganan aceate (204248-78-2 free base) 是一种阳离子抗菌肽，对革兰氏阳性菌、革兰氏阴性菌以及念珠菌均具有活性。 Omiganan aceate (204248-78-2 Free base) 是吲哚西丁的类似物，用于与酒精鼻和痤疮相关的研究目的。

Z-Cryptofolione and Cryptomoscatone D2 as highly efficacious inhibitors of the G(2) checkpoint, G(2) checkpoint inhibitors can force cells arrested in G(2) phase by DNA damage to enter mitosis. Cryptofolione shows moderate cytotoxicity in both macrophages and T. cruzi amastigotes, it also displays a mild inhibitory effect on the promastigote form of Leishmania spp.