slc39a 6

Expression system: Baculovirus Insect Cells
Length: 29-325, Partial
Activity: ELISA

SLC39A6 Protein, Rat, Recombinant (HEK293, His) is expressed in in vitro E. coli expression system. The accession number is Q4V887.

SLC39A6 Protein, Macaca fascicularis, Recombinant (His) is expressed in in vitro E. coli expression system. The accession number is XP_005586923.1.

Expression system: HEK293 Cells
Length: 29-325, Partial
Activity: ELISA

Along with the SLC30 family, SLC39 family members regulate zinc movement in cells. SLC39 metal ion transporters accumulate zinc into the cytosol. SLC39A6, also known as LIV-1, belongs to a new subfamily of Zrt, Irt-like protein zinc transporters (LZTs). It is involved in maintaining the intracellular homeostasis of zinc, an ion that is essential in the control of cellular growth and differentiation. SLC39A6 plays a critical role in maintaining zinc homeostasis, and was originally identified as an estrogen-induced gene in a breast cancer cell line. Generally, elevated SLC39A6 expression is reportedly related to cancer progression in other various types of cancer, including breast, prostate, pancreatic, cervical and liver cancers.