dbco-nhs ester

DBCO-NHS ester 是一种 ADC 连接剂，可裂解的 3 单元 PEG，还可以用于合成抗体药物共轭物 (ADC)。

DBCO-NHS ester 2 is a cleavable linker employed in the synthesis of antibody-drug conjugates (ADCs). It is a Dibenzylcyclooctyne (DBCO) derivative specifically designed for application in copper-free click chemistry [1].

DBCO-NHS ester 3 (Compound 12) is a cleavable linker utilized in the synthesis of antibody-drug conjugate (ADC). It is a derivative of Dibenzylcyclooctyne (DBCO) resulting from the activation of N-hydroxysuccinimide by the carboxylic acid moiety of both methyl-oxanorbornadiene (MeOND) and dibenzoazacyclooctyne (DIBAC)[1][2].

DBCO-PEG3-NHS ester是一种可降解的 ADC linker，可用于合成抗体偶联活性分子 。

DBCO-acid is a cleavable ADC linker utilized in the synthesis of ADC linker DBCO-NHS ester and drug-linker conjugates DBCO-PEG-MMAE[1].

DBCO-NHCO-PEG4-NHS ester ester is a MMP-2- and cathepsin B- (CatB) cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

DBCO-NHCO-PEG5-NHS ester is a polyethylene glycol (PEG)-based linker utilized in the synthesis of PROTACs[1].

DBCO-PEG4-NHS ester 是一种属于 PEG 类的 PROTAC linker，可用于 PROTAC 分子的合成。

DBCO-PEG5-NHS ester 是一种属于 PEG 类和 Alkyl/ether 类的 PROTAC linker，用于合成一系列 PROTAC 分子。

DBCO-Sulfo-NHS ester sodium 是一种可降解的 ADC linker，可用于合成 ADC 化合物。

DBCO-CONH-S-S-NHS ester is a disulfide-linked ADC linker employed for the synthesis of antibody-drug conjugates (ADCs)[1].

DBCO-NH-PEG7-C2-NHS ester is a polyethylene glycol (PEG) derived linker that possesses a terminal DBCO moiety. It functions as an N-hydroxysuccinimide (NHS) ester, making it suitable for the efficient synthesis of proteolysis-targeting chimeras (PROTACs)[1].

DBCO-NHCO-C4-NHS ester is an alkyl chain-derived PROTAC linker applicable for PROTACs synthesis[1].

DBCO-NHCO-PEG13-NHS ester is a pegylated PROteolysis-TArgeting Chimera (PROTAC) linker, serving as a valuable tool for PROTAC synthesis[1].

DBCO-NHCO-PEG2-NHS ester, a PEG-based PROTAC linker, enables the synthesis of PROTACs[1].

DBCO-NHCO-S-S-NHS ester is a cleavable linker employed for the synthesis of antibody-drug conjugates (ADCs)[1].

DBCO-PEG1-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

DBCO-PEG12-NHS ester是一种PEG类的PROTAC linker，可用于合成PROTAC分子，其DBCO基可以和含有Azide基团的分子发生点击化学反应。

DBCO-PEG8-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

N-DBCO-N-bis(PEG2-C2-NHS ester)是一种PEG类的PROTAC linker，可用于合成 PROTAC 分子，同时含有DBCO基团，可以和Azide基团发生点击化学反应。

Azido-PEG36-NHS ester 是一种 PROTAC linker，属于 PEG 类，用于合成 PROTAC 分子。作为点击化学试剂，其含有 Azide 基团，可与含有 Alkyne 基团的分子通过铜催化叠氮-炔环加成反应（CuAAc)进行反应。此外，它也可以与含有 DBCO 或 BCN 基团的分子通过环张力驱动的炔-叠氮环加成反应 (SPAAC) 结合。

Azido-PEG7-NHS ester 是一种属于PEG类的PROTAC linker，用于合成PROTAC分子。这种化合物是点击化学试剂，具有Azide基团，可以与含有Alkyne基团的分子进行铜催化的叠氮-炔环加成反应（CuAAc）。此外，它还能与含有DBCO或BCN基团的分子进行环张力驱动的炔-叠氮环加成反应（SPAAC）。

DBCO-PEG13-NHS ester 是一种 PROTAC linker，属于 PEG 类，适用于合成 PROTAC 分子。作为一种点击化学试剂，DBCO-PEG13-NHS ester 含有 DBCO 基团，可通过环张力 (strain) 促进的炔-叠氮环加成反应 (SPAAC) 与含有 Azide 基团的分子反应。

3-Azidopropionic Acid Sulfo-NHS Ester is a water-soluble compound containing an azide group and an NHS ester. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The NHS ester can be used to label the p