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96

抑制剂 & 化合物

19

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T22408	Proflavine 吡啶-3,6-二胺,3,6-Diaminoacridine	Antibacterial	Microbiology/Virology
	Proflavine (3,6-Diaminoacridine) 是吖啶染料，可用作抗菌剂。它是 DNA 嵌入剂，能够阻滞Kir3.2孔。它用作与 Kir3.2 相关的神经系统疾病的研究。
T9020	GSK620	Epigenetic Reader Domain	Chromatin/Epigenetic
	GSK620 是一种有口服活性的泛BD2抑制剂，在人全血中表现出抗炎表型，有良好的广谱选择性、可开发性和体内口服药代动力学。它对 BET-BD2 家族蛋白具有高度选择性，其选择性超过所有其他 BET 溴结构域 200 倍以上。
T12997	SR-318	p38 MAPK; TNF	Apoptosis; MAPK
	SR-318 是p38 MAPK 的选择性抑制剂，对 p38α，p38β 和 p38α/β 的IC50分别为 5 nM，32 nM 和 6.11 μM。它有效抑制全血中TNF-α的释放，IC50为 283 nM。它显示出抗癌和抗炎活性。
T8372	VU0134992 VU 0134992	Potassium Channel	Membrane transporter/Ion channel
	VU 0134992 是一个亚型偏好的，口服有效的和选择性的内向整流钾通道 Kir4.1阻滞剂，IC50为 0.97 μM。在 -120 mV 时，VU0134992对同分 Kir4.1 比 Kir4.1/5.1 共分通道 (IC50=9 μM) 高出 9 倍的选择性。
T13316	VU0134992 hydrochloride	Potassium Channel	Membrane transporter/Ion channel
	VU0134992 hydrochloride 是一个亚型偏好的，具有口服活性和选择性的内向整流钾通道Kir4.1阻滞剂，IC50为 0.97 μM。在 -120 mV 时，VU0134992 hydrochloride 对同分 Kir4.1 比 Kir4.1/5.1 共分通道 (IC50=9 μM) 高出 9 倍的选择性。
T14975	CJ-42794 CJ-042794	Others	Others
	CJ-42794 (CJ-042794)是前列腺素受体 EP4的选择性拮抗剂, 抑制[3H]-PGE2与 EP4受体结合的平均 pKi 为8.5, 对 EP4选择性比 EP1, EP2和 EP3高200多倍。
T0438	Proflavine Hemisulfate 3,6-Diaminoacridine hemisulfate,Proflavin hemisulfate,硫酸原黄素	Others; Potassium Channel; DNA; Thrombin; Antibacterial; Autophagy	Autophagy; DNA Damage/DNA Repair; Membrane transporter/Ion channel; Microbiology/Virology; Others; Proteases/Proteasome
	Proflavine Hemisulfate (3,6-Diaminoacridine hemisulfate) 是一种 DNA 嵌入剂，也是一种吖啶染料。它是抗菌剂，也可作为 Kir3.2孔阻滞剂，可研究与 Kir3.2 相关的神经系统疾病。
T6658	SB-408124 N-(6,8-二氟-2-甲基-4-喹啉)- N-[4-(二甲氨基)苯基]尿素	OX Receptor	GPCR/G Protein; Neuroscience
	SB408124 是一种 OX1 受体的非肽拮抗剂，在全细胞和膜中的 Ki 值分别为 57 和 27 nM，其选择性是 OX2 受体的 50 倍。
T32824	LM-1685 LM 1685,LM1685	COX	Immunology/Inflammation; Neuroscience
	LM-1685是一种有效且具有选择性的人单核细胞和全血中COX-2抑制剂，IC50分别为0.65 µM 和IC50 = 4.3 μM，是治疗炎症的潜在化合物。
T10866	Cot inhibitor-2	TNF; MAPK	Apoptosis; MAPK
	Cot inhibitor-2 是一种 cot (Tpl2/MAP3K8) 抑制剂(IC50 : 1.6 nM)，具有有效性，选择性和口服活性。Cot inhibitor-2 对LPS 刺激的人全血中 TNF-α 的产生具有抑制作用，IC50 为 0.3 μM。
T26531	ABT-963 ABT963
	ABT-963 is a cyclooxygenase 2 (COX-2) inhibitor potentially for the treatment of osteoarthritis and pain. ABT-963 has excellent selectivity in human whole blood, high oral anti-inflammatory potency in vivo, and gastric safety in the animal studies.
T31213	Dazmegrel UK-38,485,UK 38485,UK 38,485,UK38,485,UK-38485	PPAR	DNA Damage/DNA Repair; Metabolism
	Dazmegrel (UK 38,485) 是一种强效特异性血栓素 A2（TXA2）合成酶抑制剂，可用于预防正常妊娠中全血小板聚集增加。
T76874	Erenumab AMG-334	CGRP Receptor	GPCR/G Protein; Neuroscience
	Erenumab是一种全人单克隆抗体，作用于抑制降钙素基因相关肽(CGRP)受体，用于预防发作性偏头痛。
T77018	Garadacimab CSL312	Factor Xa	Metabolism
	Garadacimab (CSL312) 是有效的全人 IgG4 单克隆抗体，针对活化因子 XII (FXIIa)。Garadacimab 可用于研究遗传性血管性水肿。。
T77747	Adecatumumab MT 201	Others	Others
	Adecatumumab ( MT201) 是全人针对人 EpCAM 的 IgG1 单克隆抗体。Adecatumumab 具有潜在的抗癌活性，可用于研究乳腺癌。
T4367	Mycro 3 Mycro-3	c-Myc; Autophagy	Autophagy; Cell Cycle/Checkpoint
	Mycro 3 在全细胞分析中对 c-Myc 具有强效选择性，可用于胰腺癌的研究。
T10865L	Cot inhibitor-1 hydrochloride Cot inhibitor-1 hydrochloride(915365-57-0 Free base)	TNF; MAPK	Apoptosis; MAPK
	Cot inhibitor-1 hydrochloride 是肿瘤进展位点 2 激酶 (IC50 = 28 nM) 的抑制剂，可抑制人全血中 TNF-α 的产生 (IC50 = 5.7 nM)。
T37891L	GLP-1(32-36)amide acetate GLP-1(32-36)amide 醋酸盐,GLP-1(32-36)amide acetate(1417302-71-6 Free base)	Others	Others
	GLP-1(32-36)amide acetate 是一种五肽，衍生自糖调节激素 GLP-1 的 C 末端。GLP-1(32-36)amide acetate 可抑制糖尿病小鼠的体重增加并调节全身葡萄糖代谢。
T11149	Ecopladib PLA 725	Phospholipase	Metabolism
	Ecopladib (PLA 725) 是一种胞浆磷脂酶 A2α (phospholipase A2α) 抑制剂，在 GLU micelle 和大鼠全血细胞中，IC50 值分别为 0.15 μM 和 0.11 μM。
T21230	Butyl decanoate Butyl caprate,AI3-33573,Decanoic acid, butyl ester
	Butyl decanoate could substitute hazardous compounds used in tissue processing and dewaxing, along with other compounds without impairing the diagnostic value of the tissue sections. It is also used as an internal standard to calculate the acid concentrat
T16383	Olinciguat IW-1701	Guanylate cyclase	GPCR/G Protein
	Olinciguat (IW-1701) 是一种口服鸟苷酸环化酶 (sGC) 刺激剂，在纯化的大鼠和人类酶测定以及全细胞测定中对 sGC 具有浓度依赖性刺激作用。
T68155	Tebufelone	Prostaglandin Receptor; LTR	GPCR/G Protein; Immunology/Inflammation
	Tebufelone 是一种体外高效的CO 抑制剂，是一种新型的非甾体抗炎药（NSAID），属于二叔丁基苯酚（DTBP）类，在各种动物模型中显示出强大的抗炎、镇痛和抗网膜炎特性。Tebufelone 能有效地抑制前列腺素（PGE2）的形成，阻止大鼠巨噬细胞（IC50 = 20 microM）和人类全血（IC50 = 22 microM）中脂氧酶途径的产物[白三烯（LTB4）]的体外形成。
T77019	Garetosmab REGN 2477	TGF-beta/Smad	Stem Cells
	Garetosmab (REGN 2477) 是一种全人 IgG4 单克隆抗体，可选择性抑制激活素 A (activin A)，可作用于 COVID-44。Garetosmab 具有潜在的抗癌活性，可用于研究骨化性纤维发育不良 (FOP) 和癌症。
T3631	PF-8380	PDE	Metabolism
	PF8380 是有效的autotaxin 抑制剂，在体外酶实验和人类全血细胞实验中的IC50分别为 2.8 nM 和 101 nM。
T22698	TLR3-IN-1 CU CPT 4a	TLR	Immunology/Inflammation
	TLR3-IN-1 (CU CPT 4a) 是一种选择性的TLR3信号抑制剂，在 RAW 264.7 细胞中 IC50 为 3.44 μM。它可以抑制 TLR3/dsRNA 复合物介导的下游信号通路，并抑制全细胞中 TNF-α 和 IL-1β 的产生。
T23394	SR 57227A SR57227盐酸盐,SR 57227 hydrochloride	5-HT Receptor	GPCR/G Protein; Neuroscience
	SR 57227A (SR 57227 hydrochloride) 是一种有效的、具有口服活性和选择性的 5-HT3 受体激动剂，具有穿越血脑屏障的能力和抗抑郁作用。它对大鼠皮质膜和整个 NG 108-15 细胞或其膜上的 5-HT3 受体结合位点的亲和力，IC50在 2.8 至 250 nM 之间。
T76870	Narsoplimab OMS 721	SARS-CoV	Microbiology/Virology
	Narsoplimab (OMS 721) 是一种选择性全人免疫球蛋白γ 4 (IgG4) 单克隆抗体，是一种甘露聚糖结合凝集素相关的丝氨酸蛋白酶-2（MASP-2）抑制剂，可结合 MASP-2 并阻止凝集素通路激活，对凝集素通路有抑制作用。Narsoplimab 可用于研究成人造血干细胞移植相关疾病。
T10865	Cot inhibitor-1	TNF; MAPK	Apoptosis; MAPK
	Cot inhibitor-1 是一种选择性的 Cot 蛋白激酶(也被称为 Tpl2或 MAP3K8)抑制剂(IC50 为 28 nM)。Cot inhibitor-1 抑制人全血中 TNF-alpha 的产生，其 IC50 为 5.7 nM。Cot 参与多种细胞信号通路，特别是与炎症和免疫反应有关的信号通路。Cot inhibitor-1抑制 Cot 活性，可能对类风湿关节炎、炎症性肠病和某些类型的癌症具有潜在的治疗效果。
T9495	Haloxyfop methyl ester	Others	Others
	Haloxyfop methyl ester 是一种选择性除草剂，脂肪酸合成抑制剂，具有内吸作用。茎叶经处理后，迅速被杂草吸收并传递至全株，水解成酸，抑制根、茎分生组织的生长，导致死亡。
T36503	Sodium Hydrogen Sulfide (hydrate)	Others	Others
	Sodium Hydrogen Sulfide (hydrate) 与一氧化氮一样，是一种重要的气体介质，对哺乳动物的免疫、神经、心血管和肺系统有重要影响。Sodium Hydrogen Sulfide (hydrate)是一种H2S 供体，常用于细胞和整个动物实验系统。例如，它被用来证明H2S 促进中性粒细胞迁移，减少气道炎症，保护神经轴突、心脏和肠道免受化学或缺血再灌注损伤。
T0463	Loxoprofen Loxoprofene,洛索洛芬,Loxoprofeno,Koloxo	COX	Immunology/Inflammation; Neuroscience
	Loxoprofen (Koloxo) 是一种非甾体类抗炎药，具有解热作用，可用于缓解疼痛的研究。它是非选择性COX 抑制剂，对 COX-1 和 COX-2 的IC50分别为 6.5 和 13.5 μM。
T14374	AZD2906
	AZD2906, a selective glucocorticoid receptor (GR) agonist, demonstrates inhibitory concentrations (IC50s) of 2.2 nM in human GR, 0.3 nM in rat peripheral blood mononuclear cells (PBMC), 41.6 nM in human whole blood, and 7.5 nM in rat whole blood, respectively[1]. Additionally, it induces an increase in micronucleated immature erythrocytes within rat bone marrow.
T12844	SB-408124 Hydrochloride	Others	Others
	SB-408124 Hydrochloride is a non-peptide OX1 receptor antagonist(Ki of 57 nM and 27 nM in both whole cell and membrane, respectively).
T14381	AZD7624 AZD-7624	p38 MAPK; TNF	Apoptosis; MAPK
	AZD7624 是一种 p38 抑制剂，具有强大的抗炎活性。
T34580	Schweinine
	Schweinine is a macrocylic alkaloid isolated from the whole plant of Schweinfurthia papilionacea.
T61446	BioA-IN-13
	BioA-IN-13 is a highly effective inhibitor of the Mycobacterium tuberculosis BioA enzyme, displaying potent cell permeability and whole-cell activity [1].
T31432	Dicarboxidine
	Dicarboxidine can be used in immunochromatographic assay of theophylline in whole blood.
T11243	Ethyl tosylcarbamate	Others	Others
	Gliclazide is a whole-cell beta-cell ATP-sensitive potassium currents blocker with an IC50 of 184 nM. Ethyl tosylcarbamate is an intermediate in the synthesis of Gliclazide (G409877).
T23155	Piefeltarraenin ⅠB	Others	Others
	Piefeltarraenin ⅠB is extracted from the whole herb of Picriafel-terrae Lour.
T24307	L 652343 L652343,L 652,343,L652,343,L-652,343,L-652343
	L 652343 is an inhibitor of cyclooxygenase and 5-lipoxygenase in vitro. It also inhibits the synthesis of the products of both these pathways in whole cells.
T30990	CMFDA 5-Chloromethylfluorescein diacetate,Cell Tracker Green,CM-FDA,CM FDA
	CMFDA can be used as a fluorescent whole-cell-tracking reagent.
T33407	MitoEbselen-2 chloride MitoPeroxidase-2,MitoPeroxidase 2,MitoEbselen 2,MitoEbselen-2
	MitoEbselen-2 is a radiation mitigator which reduces lipid hydroperoxides and prevents apoptotic cell death. When administered 24 hours postirradiation, MitoEbselen-2 was shown to increase the survival of mice exposed to whole body γ-irradiation.
T40650	Dihydroisopimaric acid
	Dihydroisopimaric acid activates BK channels alphabeta1, which are large conductance Ca 2+ activated K + channels. This compound directly measures the opening of BKalphabeta1 under a whole-cell voltage clamp.
T38138	ACEA 2'-chloro-AEA,Arachidonoyl 2'-Chloroethylamide
	Arachidonoyl 2-chloroethylamide (ACEA) is a potent and selective cannabinoid (CB) receptor 1 agonist with Ki values of 1.4 and >2,000 nM for CB1 and CB2 receptors, respectively. In whole animal experiments, ACEA induces hypothermia in mice with the same efficacy as arachidonoyl ethanolamide , in spite of its higher affinity for the CB1 receptor. These data have been interpreted to indicate that ACEA may be a substrate for fatty acid amide hydrolase (FAAH), and thus only transiently available in ...
T35725	4-hydroxy Valsartan
	4-hydroxy Valsartan is a major metabolite of the angiotensin II type 1 (AT1) receptor antagonist valsartan . It reduces platelet aggregation induced by epinephrine and collagen but not ADP in human whole blood.
T38216	1-Palmitoyl-2-Oleoyl-3-Arachidonoyl-rac-glycerol
	1-Palmitoyl-2-oleoyl-3-arachidonoyl-rac-glycerol is a triacylglycerol that contains palmitic acid , oleic acid , and arachidonic acid at the sn-1, sn-2, and sn-3 positions, respectively. It has been found in lipid extracts from whole rat retina.1
T33424	MK-0952 MK 0952
	MK-0952 is a selective PDE4 inhibitor used to treat long-term memory loss and mild cognitive impairment. It is an intrinsically potent inhibitor and has shown limited whole blood activity.
T24188	J-104871 UNII-6137X5QNJF,J 104871
	J-104871 is an FTase inhibitor. J-104871 inhibits FTase in an FPP-competitive manner in whole cells as well as in the in vitro system. J-104871 suppressed tumor growth in nude mice transplanted with activated H-ras-transformed NIH3T3 cells.
T16477	PF-03715455	p38 MAPK	MAPK
	PF-03715455 potently inhibits LPS-induced TNFα production in human whole blood (IC50=1.7 nM). PF-03715455 is an effective inhibitor of inhaled p38 MAPK. PF-03715455 displays some selectivity for p38α over p38β (respective IC50: 0.88 and 23 nM). PF-0371545
T37763	BTD
	Selective TRPC5 activator (EC50 = 1.4 μM in a calcium influx assay, 1.3 μM in whole cell patch clamp assay). Displays >14.5-fold selectivity for TRPC5 over other TRP channels (EC50 = 20.6 μM for TRPM8). Also activates TRPC1:5 and TRPC4:5 heteromers. Beckmann et al (2017) A benzothiadiazine derivative and methylprednisolone are novel and selective activators of transient receptor potential canonical 5 (TRPC5) channels. Cell Calcium. 66 10 PMID:28807145

化合物

Cat.No: T22408

Synonym: 吡啶-3,6-二胺,3,6-Diaminoacridine

Target: Antibacterial

Cat.No: T9020

Target: Epigenetic Reader Domain

Cat.No: T12997

Target: p38 MAPK, TNF

Cat.No: T8372

Synonym: VU 0134992

Target: Potassium Channel

VU0134992 hydrochloride

Cat.No: T13316

Target: Potassium Channel

Cat.No: T14975

Synonym: CJ-042794

Target: Others

Proflavine Hemisulfate

Cat.No: T0438

Synonym: 3,6-Diaminoacridine hemisulfate,Proflavin hemisulfate,硫酸原黄素

Target: Others, Potassium Channel, DNA, Thrombin, Antibacterial, Autophagy

Cat.No: T6658

Synonym: N-(6,8-二氟-2-甲基-4-喹啉)- N-[4-(二甲氨基)苯基]尿素

Target: OX Receptor

Cat.No: T32824

Synonym: LM 1685,LM1685

Target: COX

Cot inhibitor-2

Cat.No: T10866

Target: TNF, MAPK

Cat.No: T26531

Synonym: ABT963

Cat.No: T31213

Synonym: UK-38,485,UK 38485,UK 38,485,UK38,485,UK-38485

Target: PPAR

Cat.No: T76874

Synonym: AMG-334

Target: CGRP Receptor

Cat.No: T77018

Synonym: CSL312

Target: Factor Xa

Cat.No: T77747

Synonym: MT 201

Target: Others

Cat.No: T4367

Synonym: Mycro-3

Target: c-Myc, Autophagy

Cot inhibitor-1 hydrochloride

Cat.No: T10865L

Synonym: Cot inhibitor-1 hydrochloride(915365-57-0 Free base)

Target: TNF, MAPK

GLP-1(32-36)amide acetate

Cat.No: T37891L

Synonym: GLP-1(32-36)amide 醋酸盐,GLP-1(32-36)amide acetate(1417302-71-6 Free base)

Target: Others

Cat.No: T11149

Synonym: PLA 725

Target: Phospholipase

Butyl decanoate

Cat.No: T21230

Synonym: Butyl caprate,AI3-33573,Decanoic acid, butyl ester

Cat.No: T16383

Synonym: IW-1701

Target: Guanylate cyclase

Cat.No: T68155

Target: Prostaglandin Receptor, LTR

Cat.No: T77019

Synonym: REGN 2477

Target: TGF-beta/Smad

Cat.No: T3631

Target: PDE

Cat.No: T22698

Synonym: CU CPT 4a

Target: TLR

Cat.No: T23394

Synonym: SR57227盐酸盐,SR 57227 hydrochloride

Target: 5-HT Receptor

Cat.No: T76870

Synonym: OMS 721

Target: SARS-CoV

Cot inhibitor-1

Cat.No: T10865

Target: TNF, MAPK

Haloxyfop methyl ester

Cat.No: T9495

Target: Others

Sodium Hydrogen Sulfide (hydrate)

Cat.No: T36503

Target: Others

Cat.No: T0463

Synonym: Loxoprofene,洛索洛芬,Loxoprofeno,Koloxo

Target: COX

Cat.No: T14374

SB-408124 Hydrochloride

Cat.No: T12844

Target: Others

Cat.No: T14381

Synonym: AZD-7624

Target: p38 MAPK, TNF

Cat.No: T34580

Cat.No: T61446

Cat.No: T31432

Ethyl tosylcarbamate

Cat.No: T11243

Target: Others

Piefeltarraenin ⅠB

Cat.No: T23155

Target: Others

Cat.No: T24307

Synonym: L652343,L 652,343,L652,343,L-652,343,L-652343

Cat.No: T30990

Synonym: 5-Chloromethylfluorescein diacetate,Cell Tracker Green,CM-FDA,CM FDA

MitoEbselen-2 chloride

Cat.No: T33407

Synonym: MitoPeroxidase-2,MitoPeroxidase 2,MitoEbselen 2,MitoEbselen-2

Dihydroisopimaric acid

Cat.No: T40650

Cat.No: T38138

Synonym: 2'-chloro-AEA,Arachidonoyl 2'-Chloroethylamide

4-hydroxy Valsartan

Cat.No: T35725

1-Palmitoyl-2-Oleoyl-3-Arachidonoyl-rac-glycerol

Cat.No: T38216

Cat.No: T33424

Synonym: MK 0952

Cat.No: T24188

Synonym: UNII-6137X5QNJF,J 104871

Cat.No: T16477

Target: p38 MAPK

Cat.No: T37763

Cat. No.	Product Name	Target	Signaling Pathways
T3S0693	Blinin	Others	Others
	Blinin 是一种二萜，分离自植物 Conyza blinii 中。
TN7077	Sinocrassoside C1	Others	Others
	Sinocrassoside C1 是中国景天（景天科）全植物的甲醇提取物。
T5730	MALTOHEXAOSE Amylohexaose,麦芽六糖	Others; Endogenous Metabolite	Metabolism; Others
	Maltohexaose (Amylohexaose) 是天然糖类，能够由直链淀粉、支链淀粉和全淀粉产生。
TN2079	(-)-Pinoresinol	Others; TNF; NF-κB; COX	Apoptosis; Immunology/Inflammation; Neuroscience; NF-κB; Others
	(-)-Pinoresinol 是从 Serissa japonica (Thunb.) Thunb 的全植物中分离得到的天然产物。
T0570	3,5-Dihydroxybenzoic acid	Others; Endogenous Metabolite	Metabolism; Others
	3,5-Dihydroxybenzoic acid 是烷基间苯二酚在人尿和血浆中的代谢物，是啤酒，坚果，花生和豆类等食物摄入的潜在生物标记。
T2758	Madecassic acid 6-Deoxy-L-Galactose,羟基积雪草酸,L-Fucose,Brahmic acid,L-fucopyranose	Others; TNF; COX; NO Synthase; Interleukin	Apoptosis; Immunology/Inflammation; Neuroscience; Others
	Madecassic acid (L-fucopyranose) 是分离自积雪草的一种天然产物，抑制iNOS、COX-2、TNF-α、IL-1beta 和IL-6，可通过在 RAW 264.7 巨噬细胞中下调NF-κB 激活而具有抗炎作用。
T4785	Oxfenicine 4-羟基-L-苯甘氨酸,4-Hydroxy-L-phenylglycine	Others	Others
	Oxfenicine (4-Hydroxy-L-phenylglycine) 是具有口服活性的肉碱棕榈酰转移酶-1 抑制剂。它在缺血期间保护心脏免受坏死组织的损害。它可抑制心脏中脂肪酸的氧化。
TN1433	Batatasin III	FAK; Others; Akt	Angiogenesis; Cytoskeletal Signaling; Others; PI3K/Akt/mTOR signaling; Tyrosine Kinase/Adaptors
	Batatasin III 通过抑制上皮间质转化和 FAK-AKT 信号来抑制癌症迁移和侵袭，并具有抗癌活性。 Batatasin III 对整株生长有长期抑制作用，显示出抑制萌发活性。
T2985	Gypenoside XLIX 绞股蓝皂苷 XLIX,绞股蓝皂苷XLIX	PPAR	DNA Damage/DNA Repair; Metabolism
	Gypenoside XLIX 是一种达玛烷型糖苷，是绞股蓝的主要成分。它是选择性过氧化物酶体增殖物激活受体 (PPAR)-α激活剂，可抑制细胞因子诱导的血管细胞粘附分子-1 (VCAM-1) 在人体内皮细胞中过度活跃和表达。
T4716	Pyrrole-2-carboxylic acid 吡咯-2-羧酸,2-Pyrrolecarboxylic acid,Minaline	Endogenous Metabolite	Metabolism
	Pyrrole-2-carboxylic acid (Minaline) 是一种天然生物碱类，从海洋细菌Pelomonas puraquaesp. Nov 中分离得到。
T36914	2-Hydroxyanthraquinone	Others	Others
	2-Hydroxyanthraquinone 是一种天然产物，显示出抗肿瘤和免疫抑制活性。
T7786	Tryptanthrin	DNA gyrase	DNA Damage/DNA Repair
	Tryptanthrin 是一种口服具有活性的细胞内Leukotriene (LT) biosynthesis 抑制剂。它能够降低大鼠胸膜炎模型中的 LTB4 水平，并抑制人全血中Leukotriene 的形成 (IC50= 10 µM)。
TN1016	Kukoamine A	NF-κB; Lipoxygenase; DNA/RNA Synthesis; Parasite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Microbiology/Virology; NF-κB
	Kukoamine A 是一种天然的精胺衍生物，具有抗癌、抗高血压、细胞保护、抗氧化和抗炎活性。它是锥虫硫磷还原酶抑制剂，Ki 值为 1.8 μM。
TN5661	1,7-Bis(4-hydroxyphenyl)-3-hydroxy-1,3-heptadien-5-one
	1,7-Bis(4-hydroxyphenyl)-3-hydroxy-1,3-heptadien-5-one shows strong inhibition of collagen-induced, arachidonic acid-induced, and adenosine diphosphate-induced platelet aggregation of human whole blood.
T3242	Breviscapin Scutellarin,红盏花素,Scutellarin B	Others	Others
	Breviscapin (Scutellarin) 是从Erigeron breviscapus 全草中提取的总黄酮成分(含量≥85%)。
TN4297	Isohomoarbutin	Others	Others
	Isohomoarbutin 是来自 Pyrola rotundifolia (Pyrolaceae) 全草本植物的天然产物。
T40193	Ebeiedinone
	Ebeiedinone, a steroidal alkaloid derived from Fritillaria species, effectively inhibits the activity of human whole blood cholinesterase (ChE) at a concentration of 0.1 mM, resulting in a significant inhibitory effect of 69.0%.
T81956	Ladanetin-6-O-β-(6′′-O-acetyl)glucoside
	Ladanetin-6-O-β-(6′′-O-acetyl)glucoside 是一种从甘青青兰 (Dracocephalum tanguticum) 全株中提取的黄酮化合物，具备抗氧化特性。该化合物能够保护H9c2心肌细胞免受Doxorubicin(DOX)引起的细胞毒性。
T80002	Wulfenioidin F	Virus Protease	Microbiology/Virology
	Wulfenioidin F是从Orthosiphon wulfenioides全草分离的二萜类化合物。该化合物对抗寨卡病毒(ZIKV)活性显著，其半数有效浓度(EC50)为8.07 μM。Wulfenioidin F的抗病毒机制通过抑制ZIKV包膜(E)蛋白的表达，从而干扰病毒复制。

天然产物

Cat.No: T3S0693

Target: Others

Sinocrassoside C1

Cat.No: TN7077

Target: Others

Cat.No: T5730

Synonym: Amylohexaose,麦芽六糖

Target: Others, Endogenous Metabolite

(-)-Pinoresinol

Cat.No: TN2079

Target: Others, TNF, NF-κB, COX

3,5-Dihydroxybenzoic acid

Cat.No: T0570

Target: Others, Endogenous Metabolite

Madecassic acid

Cat.No: T2758

Synonym: 6-Deoxy-L-Galactose,羟基积雪草酸,L-Fucose,Brahmic acid,L-fucopyranose

Target: Others, TNF, COX, NO Synthase, Interleukin

Cat.No: T4785

Synonym: 4-羟基-L-苯甘氨酸,4-Hydroxy-L-phenylglycine

Target: Others

Cat.No: TN1433

Target: FAK, Others, Akt

Gypenoside XLIX

Cat.No: T2985

Synonym: 绞股蓝皂苷 XLIX,绞股蓝皂苷XLIX

Target: PPAR

Pyrrole-2-carboxylic acid

Cat.No: T4716

Synonym: 吡咯-2-羧酸,2-Pyrrolecarboxylic acid,Minaline

Target: Endogenous Metabolite

2-Hydroxyanthraquinone

Cat.No: T36914

Target: Others

Cat.No: T7786

Target: DNA gyrase

Cat.No: TN1016

Target: NF-κB, Lipoxygenase, DNA/RNA Synthesis, Parasite

1,7-Bis(4-hydroxyphenyl)-3-hydroxy-1,3-heptadien-5-one

Cat.No: TN5661

Cat.No: T3242

Synonym: Scutellarin,红盏花素,Scutellarin B

Target: Others

Cat.No: TN4297

Target: Others

Cat.No: T40193

Ladanetin-6-O-β-(6′′-O-acetyl)glucoside

Cat.No: T81956

Cat.No: T80002

Target: Virus Protease

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