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Search Results for " c17 "

15

抑制剂 & 化合物

3

天然产物

8

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T38182	C17 Sphingomyelin (d18:1/17:0) C17 Sphingomyelin (d18:1/17:0)
	C17 Sphingomyelin is a synthetic derivative of sphingomyelin that has been used as an internal standard for the quantification of sphingomyelin.
T37438	C17 Globotriaosylceramide (d18:1/17:0) C17 Globotriaosylceramide (d18:1/17:0)
	C17 Globotriaosylceramide is a sphingolipid that has been used as an internal standard for the quantification of globotriaosylceramides in plasma and urine from patients with Fabry disease by GC-MS.
T37437	C17 Ceramide (d18:1/17:0)
	C17 Ceramide is a synthetic ceramide that contains a non-natural C17:0 fatty acid acylated to sphingosine. It has been used as a marker of arylsulfatase A and sphingolipid activator B activity in patients undergoing enzyme replacement therapy for the genetic disease metachromatic leukodystrophy.
T38181	C17 Lactosylceramide (d18:1/17:0)
	C17 Lactosylceramide is a naturally occurring sphingolipid that has been found in human brain metastases of lung adenocarcinomas but not in healthy brain tissue.
T69430	PRMT5-IN-C17
	PRMT5-IN-C17 is a novel potent, selective, and cell active protein arginine methyltransferase 5 (PRMT5) inhibitor.
T29112	VPC171 (2-氨基-4-(3-(三氟甲基)苯基)噻吩-3-基)(苯基)甲酮,VPC 171,VPC-171	Adenosine Receptor	GPCR/G Protein; Neuroscience
	VPC171 是一种新型腺苷 A1 受体正变构调节剂 (PAM)。
T35521	Aflatoxin G2-13C17 Aflatoxin G2-13C17
	Aflatoxin G2-13C17is intended for use as an internal standard for the quantification of aflatoxin G2by GC- or LC-MS. Aflatoxin G2is a mycotoxin that has been found inAspergillus.1It is lethal to ducklings (LD50= 2.83 mg/kg) but is non-toxic to rats when administered at a dose of 200 mg/kg.2 1.Bennett, J.W., and Klich, M.MycotoxinsClin. Microbiol. Rev.16(3)497-516(2003) 2.Wogan, G.N., Edwards, G.S., and Newberne, P.M.Structure-activity relationships in toxicity and carcinogenicity of aflatoxins a...
T27972	MAC173979 MAC-173979,MAC 173979
	MAC173979 inhibits E. coli de novo PABA biosynthesis and growth.
T24599	PC170942 Sodium PC170942 Sodium salt
	PC170942 Sodium is a water-soluble bacterial cytokinesis inhibitor that acts by inhibiting FtsZ.
T35519	Aflatoxin B2-13C17 Aflatoxin B2-13C17
	Aflatoxin B2-13C17(AFB2-13C17) is intended for use as an internal standard for the quantification of AFB2by GC- or LC-MS. AFB2is a mycotoxin that has been found inA. terricola.1It induces hepatic autophagy and apoptosis in broiler chickens when administered at doses of 0.2, 0.4, and 0.8 mg/kg.2AFB2(0.5 and 1 mg/animal) also induces parenchymal cell hyperplasia in rats.3 1.Moubasher, A.H., el-Kady, I.A., and Shoriet, A.Toxigenic Aspergilli isolated from different sources in EgyptAnn. Nutr. Alimen...
T35762	MC1742
	MC1742 is an inhibitor of class I histone deacetylases (HDACs; IC50s = 0.1, 0.11, 0.02, and 0.61 μM for HDAC1, -2, -3, and -8, respectively) and class IIb HDACs (IC50s = 7 and 40 nM for HDAC6 and HDAC10, respectively).1 It is selective for class I and class IIb over class IIa HDACs (IC50s = >50 μM for HDAC4, -5, -7, and -9). MC1742 reduces proliferation of HOS, MG-63, RD, A204, SK-ES-1, and A673 sarcoma cancer stem cells (CSCs). It increases levels of acetylated histone H3 and acetylated tubulin...
T35515	3-Acetyldeoxy Nivalenol-13C17 3-Acetyldeoxy Nivalenol-13C17
	3-Acetyldeoxy nivalenol-13C17is intended for use as an internal standard for the quantification of 3-acetyldeoxy nivalenol by GC- or LC-MS. 3-Acetyldeoxy nivalenol is a mycotoxin that has been found inF. graminearum.1In vivo, 3-acetyldeoxy nivalenol (40 mg/kg) induces duodenal and splenic cell necrosis, as well as lethality (LD50= 70 mg/kg) in mice.2 1.Jiao, F., Kawakami, A., and Nakajima, T.Effects of different carbon sources on trichothecene production and Tri gene expression by Fusarium grami...
T35520	Aflatoxin G1-13C17 Aflatoxin G1-13C17
	Aflatoxin G1-13C17is intended for use as an internal standard for the quantification of aflatoxin G1by GC- or LC-MS. Aflatoxin G1is a mycotoxin that has been found inA. terricola.1In vivo, aflatoxin G1is lethal to ducklings (LD50= 1.18 mg/kg).2It induces hepatocellular carcinoma tumor formation and lethality in rats when administered at doses of 1.4 and 3 mg/animal, respectively. Aflatoxin G1also inhibits liver and kidney succinate dehydrogenase and fumarase, as well as kidney cytochrome oxidase...
T24952	ZINC17167211 ZINC-17167211,ZINC 17167211
	ZINC17167211 is a selective peroxisome proliferator-activated receptors-α agonist.
T78764	Anticancer agent 136	Apoptosis	Apoptosis
	Anticanceragent 136 (compound 22)，一种GDM C17-三唑类似物，对HDF表现出3.38 μM的IC50，与Hsp90有3.86 μM的Kd。本化合物功能为细胞凋亡诱导剂。

化合物

C17 Sphingomyelin (d18:1/17:0)

Cat.No: T38182

Synonym: C17 Sphingomyelin (d18:1/17:0)

C17 Globotriaosylceramide (d18:1/17:0)

Cat.No: T37438

Synonym: C17 Globotriaosylceramide (d18:1/17:0)

C17 Ceramide (d18:1/17:0)

Cat.No: T37437

C17 Lactosylceramide (d18:1/17:0)

Cat.No: T38181

Cat.No: T69430

Cat.No: T29112

Synonym: (2-氨基-4-(3-(三氟甲基)苯基)噻吩-3-基)(苯基)甲酮,VPC 171,VPC-171

Target: Adenosine Receptor

Aflatoxin G2-13C17

Cat.No: T35521

Synonym: Aflatoxin G2-13C17

Cat.No: T27972

Synonym: MAC-173979,MAC 173979

PC170942 Sodium

Cat.No: T24599

Synonym: PC170942 Sodium salt

Aflatoxin B2-13C17

Cat.No: T35519

Synonym: Aflatoxin B2-13C17

Cat.No: T35762

3-Acetyldeoxy Nivalenol-13C17

Cat.No: T35515

Synonym: 3-Acetyldeoxy Nivalenol-13C17

Aflatoxin G1-13C17

Cat.No: T35520

Synonym: Aflatoxin G1-13C17

Cat.No: T24952

Synonym: ZINC-17167211,ZINC 17167211

Anticancer agent 136

Cat.No: T78764

Target: Apoptosis

Cat. No.	Product Name	Target	Signaling Pathways
T6S2116	Ginkgolic acid C17:1 银杏酸 C17:1,银杏酸C17:1	Phosphatase; PTEN	Metabolism; PI3K/Akt/mTOR signaling
	Ginkgolic acid C17:1 是分离自银杏叶中，通过诱导PTEN 和SHP-1酪氨酸磷酸酶抑制组成型和诱导型 STAT3 活化。它具有抗癌活性。
TN2373	(E/Z)-Ginkgolic acid C17:2 Ginkgolic Acid C17:2	Dehydrogenase	Metabolism
	(E/Z)-Ginkgolic acid C17:2 (Ginkgolic Acid C17:2) 是一种可从银杏中提取的天然产物，可靶向人二氢乳清酸脱氢酶 (DHODH).
T78473	Sphingosine (d17:1) C17 Sphingosine
	Sphingosine (d17:1) (C17 Sphingosine)是一种存在于人类皮肤中的17碳鞘脂，可被鞘氨醇激酶的磷酸化。Sphingosine C-17作为内标可用于进行鞘脂类化合物的光谱分析。

天然产物

Ginkgolic acid C17:1

Cat.No: T6S2116

Synonym: 银杏酸 C17:1,银杏酸C17:1

Target: Phosphatase, PTEN

(E/Z)-Ginkgolic acid C17:2

Cat.No: TN2373

Synonym: Ginkgolic Acid C17:2

Target: Dehydrogenase

Sphingosine (d17:1)

Cat.No: T78473

Synonym: C17 Sphingosine

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPK-00685	CYTL1 Protein, Mouse, Recombinant (hFc) CYTL1,C4orf4,Protein C17	Mouse	HEK293 Cells
	Cytokine-like protein 1 (Cytl1), also named Protein C17 or C4orf4 is located on human chromosome 4p15-p16 and encodes a polypeptide of 126 amino acid residues that displays characteristics of a secretory protein. Cytl1 is expressed by a sub-population of CD34 human mononuclear cells from bone marrow and cord blood, and by chondrocytes (cartilage-forming cells).
TMPY-00044	CYTL1 Protein, Human, Recombinant (mFc) C4orf4,C17,cytokine-like 1	Human	HEK293 Cells
	Cytokine-like protein 1 (CYTL1) is a small widely expressed secreted protein lacking significant primary sequence homology to any other known protein. Cytokine-like 1 (CYTL1) is a novel potential cytokine that was first identified in CD34(+) cells derived from bone marrow and cord blood, and it was also found using our immunogenomics strategy. CYTL1 expression appears to be highest in the hematopoietic system and in chondrocytes; however, maintenance of cartilage in mouse models of arthritis is ...
TMPH-02139	CYP17A1 Protein, Human, Recombinant (GST) Cytochrome P450 17A1,CYPXVII,CYP17A1,CYP17,S17AH,Cytochrome ...	Human	E. coli
	A cytochrome P450 monooxygenase involved in corticoid and androgen biosynthesis. Catalyzes 17-alpha hydroxylation of C21 steroids, which is common for both pathways. A second oxidative step, required only for androgen synthesis, involves an acyl-carbon cleavage. The 17-alpha hydroxy intermediates, as part of adrenal glucocorticoids biosynthesis pathway, are precursors of cortisol (Probable). Hydroxylates steroid hormones, pregnenolone and progesterone to form 17-alpha hydroxy metabolites, follow...
TMPJ-01456	Mucin-17/MUC17 Protein, Human, Recombinant (His) Mucin-17, MUC-17, MUC17, MUC3, MUC-3	Human	HEK293 Cells
	Mucins are key components of the mucosal barrier in the stomach that protects epithelia from carcinogenic effects of chronic inflammation. Analysis of The Cancer Genome Atlas database indicated that mucin17 (MUC17) was more highly expressed in gastric cancer (GC) specimens, with favourable prognosis for patients. And that p38 signalling is a key factor involved in MUC17-mediated inhibition of GC cell proliferation and protection against inflammatory stimulation, MUC17 upregulates the expression ...
TMPH-03400	SLC17A6 Protein, Rat, Recombinant (His)	Rat	P. pastoris (Yeast)
	Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate. Involved in the regulation of retinal hyaloid vessel regression during postnatal development. May also play a role in the endocrine glutamatergic system of other tissues such as pineal gland and pancreas. SLC17A6 Protein, Rat, Recombinant (His) is expressed in yeast with C-6xHis tag. The predicted molecular weight is 11.1 kDa an...
TMPY-02572	TXNDC17 Protein, Human, Recombinant thioredoxin domain containing 17,TXNL5,TRP14	Human	E. coli
	Thioredoxin-related protein of 14 kDa (TRP14, also called TXNDC17 for thioredoxin domain containing 17, or TXNL5 for thioredoxin-like 5) is an evolutionarily well-conserved member of the thioredoxin (Trx)-fold protein family that lacks activity with classical Trx1 substrates. TXNDC17 is a novel 14-kDa disulfide reductase of the TXN (thioredoxin) family. TXNDC17 is involved in the TNF (tumor necrosis factor) signaling pathway. Moreover, TXNDC17 plays an important role in Taxol resistance via enha...
TMPH-02195	TXNDC17 Protein, Human, Recombinant (GST)	Human	E. coli
	Disulfide reductase. May participate in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyze dithiol-disulfide exchange reactions. Modulates TNF-alpha signaling and NF-kappa-B activation. Has peroxidase activity and may contribute to the elimination of cellular hydrogen peroxide.
TMPH-01109	CCDC174 Protein, Human, Recombinant (His & Myc) C3orf19,Coiled-coil domain-containing protein 174,CCDC17...	Human	E. coli
	CCDC174 Protein, Human, Recombinant (His & Myc) is expressed in E. coli.

重组蛋白

CYTL1 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPK-00685

Species: Mouse

Expression System: HEK293 Cells

CYTL1 Protein, Human, Recombinant (mFc)

Cat.No: TMPY-00044

Species: Human

Expression System: HEK293 Cells

CYP17A1 Protein, Human, Recombinant (GST)

Cat.No: TMPH-02139

Species: Human

Expression System: E. coli

Mucin-17/MUC17 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01456

Species: Human

Expression System: HEK293 Cells

SLC17A6 Protein, Rat, Recombinant (His)

Cat.No: TMPH-03400

Species: Rat

Expression System: P. pastoris (Yeast)

TXNDC17 Protein, Human, Recombinant

Cat.No: TMPY-02572

Species: Human

Expression System: E. coli

TXNDC17 Protein, Human, Recombinant (GST)

Cat.No: TMPH-02195

Species: Human

Expression System: E. coli

CCDC174 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01109

Species: Human

Expression System: E. coli

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