表皮生长因子(Epidermal Growth Factor, EGF)是一种通过与其受体EGFR结合来刺激细胞生长和分化的蛋白质。EGF通过与细胞表面的表皮生长因子受体(EGFR)以高亲和力结合而起作用。可刺激配体诱导的二聚化,激活受体的内在蛋白-酪氨酸激酶活性。酪氨酸激酶活性反过来又启动信号转导级联反应,导致细胞内的各种生化变化,例如细胞内钙水平升高、糖酵解和蛋白质合成增加,以及某些基因(包括 EGFR 基因)表达增加,最终导致 DNA 合成和细胞增殖。
Cat. No. | Product Name / Synonyms | Species | Expression System |
---|---|---|---|
TMPJ-00058 | BTC Protein, Mouse, Recombinant (His)
BTC Protein, Mouse, Recombinant (His)
|
Mouse | E. coli |
Mouse Betacellulin is a single type I membrane protein which belongs to the EGF family of cytokines. EGF family has many members including EGF, TGF-a, Amphiregul... | |||
TMPJ-00448 | NRG1 beta 1 Protein, Human, Recombinant (aa 2-246)
NRG1 beta 1 Protein, Human, Recombinant (aa 2-246)
|
Human | E. coli |
Pro-neuregulin-1,Neuregulin-1 beta 1(NRG1) is a single-pass type I membrane protein and belongs to the neuregulin family .It contains 1 EGF-like domain and 1 Ig... | |||
TMPJ-00859 | AREG Protein, Human, Recombinant
AREG Protein, Human, Recombinant
|
Human | E. coli |
Amphiregulin (AREG) is a single-pass membrane protein with 252 amino acids. AREG belongs to the amphiregulin family, which contains 1 EGF-like domain. AREG is ex... | |||
TMPK-00757 | TGF alpha Protein, Human, Recombinant (hFc)
TGF alpha Protein, Human, Recombinant (hFc)
|
Human | HEK293 |
Transforming growth factor-alpha (TGFA) has been proposed as a candidate gene in the etiology of nonsyndromic cleft lip with or without cleft palate (NS-CL/P) an... | |||
TMPK-00820 | AREG Protein, Human, Recombinant (hFc)
AREG Protein, Human, Recombinant (hFc)
|
Human | HEK293 |
Amphiregulin (AREG) is a member of the epidermal growth factor (EGF) family and is expressed in a plethora of cancers. Tumour growth and metastasis were decrease... | |||
TMPK-00870 | AREG Protein, Mouse, Recombinant (hFc)
AREG Protein, Mouse, Recombinant (hFc)
|
Mouse | HEK293 |
Amphiregulin (AREG) is a ligand of the epidermal growth factor receptor (EGFR), a widely expressed transmembrane tyrosine kinase. AREG is synthesized as a membra... | |||
TMPK-00888 | TGF alpha Protein, Mouse, Recombinant (hFc)
TGF alpha Protein, Mouse, Recombinant (hFc)
|
Mouse | HEK293 |
Transforming growth factor-alpha (TGFA) has been proposed as a candidate gene in the etiology of nonsyndromic cleft lip with or without cleft palate (NS-CL/P) an... | |||
TMPY-00031 | Neuregulin-1/NRG1 Protein, Human, Recombinant (His)
Neuregulin-1/NRG1 Protein, Human, Recombinant (His)
|
Human | HEK293 |
Neuregulin 1 or NRG1 is one of four proteins in the neuregulin family that act on the EGFR family of receptors. This growth factor was originally identified as a... | |||
TMPY-00078 | EGFL6 Protein, Mouse, Recombinant (His)
EGFL6 Protein, Mouse, Recombinant (His)
|
Mouse | HEK293 |
EGFL6, also known as EGF-L6, belongs to the epidermal growth factor (EGF) repeat superfamily. Members of this superfamily are characterized by the presence of EG... | |||
TMPY-00094 | EGFL6 Protein, Mouse, Recombinant (hFc)
EGFL6 Protein, Mouse, Recombinant (hFc)
|
Mouse | HEK293 |
EGFL6, also known as EGF-L6, belongs to the epidermal growth factor (EGF) repeat superfamily. Members of this superfamily are characterized by the presence of EG... | |||
TMPY-00192 | NRG3 Protein, Human, Recombinant (hFc)
NRG3 Protein, Human, Recombinant (hFc)
|
Human | HEK293 |
NRG3 (Neuregulin 3) is a Protein Coding gene. NRG3 is a member of the neuregulin family of EGF proteins. It has been shown to activate the tyrosine phosphorylati... | |||
TMPY-00220 | EGF Protein, Mouse, Recombinant (His)
EGF Protein, Mouse, Recombinant (His)
|
Mouse | HEK293 |
EGF is the founding member of the EGF-family of proteins. Members of this protein family have highly similar structural and functional characteristics. EGF conta... | |||
TMPY-00343 | RTN4RL1 Protein, Human, Recombinant (hFc)
RTN4RL1 Protein, Human, Recombinant (hFc)
|
Human | HEK293 |
RTN4RL1 Protein, Human, Recombinant (hFc) is expressed in HEK293 with hFc tag. The predicted molecular weight is 71.5 kDa. Accession number: Q86UN2 | |||
TMPY-00479 | Neuregulin-1/NRG1 Protein, Human, Recombinant (hFc)
Neuregulin-1/NRG1 Protein, Human, Recombinant (hFc)
|
Human | HEK293 |
Neuregulin 1 or NRG1 is one of four proteins in the neuregulin family that act on the EGFR family of receptors. This growth factor was originally identified as a... | |||
TMPY-01323 | Betacellulin Protein, Mouse, Recombinant (His & hFc)
Betacellulin Protein, Mouse, Recombinant (His & hFc)
|
Mouse | HEK293 |
Betacellulin(BTC) is a member of the epidermal growth factor (EGF) family. These soluble proteins are ligands for one or more of the four receptor tyrosine kinas... | |||
TMPY-02166 | Epiregulin Protein, Mouse, Recombinant (hFc)
Epiregulin Protein, Mouse, Recombinant (hFc)
|
Mouse | HEK293 |
Epiregulin (EREG) is a member of the epidermal growth factor family. Epiregulin (EREG) can function as a ligand of EGFR (epidermal growth factor receptor), as we... | |||
TMPY-02169 | Epiregulin Protein, Human, Recombinant (hFc)
Epiregulin Protein, Human, Recombinant (hFc)
|
Human | HEK293 |
Epiregulin (EREG) is a member of the epidermal growth factor family. Epiregulin (EREG) can function as a ligand of EGFR (epidermal growth factor receptor), as we... | |||
TMPY-02178 | EGFL7 Protein, Mouse, Recombinant (His)
EGFL7 Protein, Mouse, Recombinant (His)
|
Mouse | Baculovirus-Insect Cells |
Epidermal growth factor-like protein 7, also known as EGF-like protein 7, Multiple epidermal growth factor-like domains protein 7, Multiple EGF-like domains pr... | |||
TMPY-02267 | EGF Protein, Mouse, Recombinant (hFc)
EGF Protein, Mouse, Recombinant (hFc)
|
Mouse | HEK293 |
EGF is the founding member of the EGF-family of proteins. Members of this protein family have highly similar structural and functional characteristics. EGF conta... | |||
TMPY-02539 | EGF Protein, Canine, Recombinant (His)
EGF Protein, Canine, Recombinant (His)
|
Canine | E. coli |
EGF is the founding member of the EGF-family of proteins. Members of this protein family have highly similar structural and functional characteristics. EGF conta... |