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- 2010种抗氧化生物活性小分子化合物的特有集合，可用于高通量、高内涵筛选；
- 靶点含mTOR, Keap1‐Nrf2, ROS, NF-κB等；
- 结构多样，药效显著，可渗透细胞；
- 详细的说明书、化合物结构、靶点信息、活性描述等；
- NMR、HPLC/LCMS等多种检测技术保证产品结构正确，纯度高，减少假阳性。
抗氧化化合物库
Antioxidant Compound Library
很棒氧化应激（Oxidative Stress，OS）是指体内氧化与抗氧化作用失衡的一种状态。氧化应激导致活性氧（ROS）大量积累，氧化程度超出抗氧化物的清除能力，从而引起氧化损伤，氧化应激损伤是许多疾病发生的基础，不同程度的氧化应激造成的细胞效应与心脑血管疾病、神经退行性病变、炎症和肿瘤密切相关。抗氧化剂是一类能够对抗氧化应激，降低氧化损伤的一类化合物。
TargetMol 抗氧化化合物库是2010 种对氧化应激具有抑制作用的小分子特有集合，是研究氧化应激的有用工具，可以用于高通量筛选和高内涵筛选。
TargetMol 的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。
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化合物库相关信息
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抗氧化化合物库规格
- 1 mg
- 10 μL x 10 mM (in DMSO)
- 20 μL x 10 mM (in DMSO)
- 30 μL x 10 mM (in DMSO)
- 50 μL x 10 mM (in DMSO)
- 100 μL x 10 mM (in DMSO)
- 250 μL x 10 mM (in DMSO)
询价 & 定制
产品描述
包装和储存
- 可选用DMSO耐受的96/384孔板或2D 条形码编码管；
- 干粉蓝冰运输，DMSO溶液干冰运输；
- 排布：96孔板：1st & 12th 空白对照，384孔板：1st & 2nd & 23th & 24th空白对照。
- 本化合物库通常以 DMSO 10 mM 浓度提供。少量产品可能因溶解性或稳定性需求，采用其他溶剂或浓度包装，具体以实际产品信息为准。
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化合物库组成
Apoptosis
ROS
NF-κB
Antioxidant
Autophagy
PI3K
Reactive Oxygen Species
Endogenous Metabolite
Antibacterial
Akt
mTOR
Prostaglandin Receptor
Cytochromes P450
AMPK
COX
TLR
Tyrosinase
TNF
Sirtuin
Antifungal
ERK
Nrf2
p38 MAPK
Parasite
Caspase
GSK-3
NO Synthase
Antibiotic
Interleukin
Tyrosine Kinases
Ferroptosis
DNA/RNA Synthesis
HIV Protease
JNK
PPAR
Influenza Virus
IL Receptor
CDK
DNA-PK
STAT
MMP
JAK
S6 Kinase
Bcl-2 Family
DNA Alkylator/Crosslinker
Calcium Channel
NOD-like Receptor (NLR)
Wnt/beta-catenin
Cholinesterase (ChE)
VEGFR
SARS-CoV
ATM/ATR
ROS Kinase
Mitophagy
Virus Protease
Dehydrogenase
Beta Amyloid
Phosphatase
HSV
PKC
Lipoxygenase
EGFR
Src
GABA Receptor
Xanthine Oxidase
Anti-infection
P-gp
PDK
Potassium Channel
NOS
AChR
Mitochondrial Metabolism
Glutathione Peroxidase
PKA
IκB/IKK
FLT
Immunology/Inflammation related
NOD
HCV Protease
Adrenergic Receptor
MAPK
Ras
HIF/HIF Prolyl-Hydroxylase
Glucosidase
glycosidase
HDAC
Antiviral
PARP
PDE
Free radical scavengers
Drug Metabolite
PGE Synthase
Reductase
Estrogen Receptor/ERR
DNA Alkylation
IGF-1R
Casein Kinase
TRP/TRPV Channel
transporter
MEK
PI4K
GPCR
ALK
FAK
HBV
5-HT Receptor
MAO
MDM-2/p53
Topoisomerase
PTEN
p53
Estrogen/progestogen Receptor
Aurora Kinase
Microtubule Associated
Monoamine Oxidase
Serine Protease
Chk
Sodium Channel
Antifection
Androgen Receptor
RAAS
Histamine Receptor
HSP
ATPase
Angiotensin-converting Enzyme (ACE)
c-Met/HGFR
Reverse Transcriptase
HIF
Bcr-Abl
Fatty Acid Synthase
Proteasome
Epigenetic Reader Domain
TGF-beta/Smad
Phospholipase
Carbonic Anhydrase
E1/E2/E3 Enzyme
PDGFR
CaMK
Syk
Adenosine Receptor
c-Myc
Leukotriene Receptor
Integrin
SIK
GluR
ROCK
NMDAR
PLK
Chloride channel
Serine/threonin kinase
Cysteine Protease
GPX
Retinoid Receptor
MLK
FGFR
LTR
iGluR
BACE
NADPH
Raf
Gamma-secretase
Trk receptor
Aromatase
MyD88
Aryl Hydrocarbon Receptor
LDL
Pyroptosis
FKBP
Dopamine Receptor
Survivin
HMG-CoA Reductase
Hedgehog/Smoothened
Beta-Secretase
c-RET
PERK
Nucleoside Antimetabolite/Analog
IAP
Transferase
Telomerase
SGLT
Thrombin
AhR
Mdm2
Liver X Receptor
Histone Acetyltransferase
MELK
GST
PD-1/PD-L1
FOXO3
RAR/RXR
Melatonin Receptor
Amylase
Prolyl Endopeptidase (PREP)
Opioid Receptor
OXPHOS
Acetyl-CoA Carboxylase
Cannabinoid Receptor
NADPH-oxidase
Histone Methyltransferase
MRP
PYK2
RIP kinase
UGT
Indoleamine 2,3-Dioxygenase (IDO)
BCRP
Kinesin
NPC1L1
Cholecystokinin Receptor
Myosin
FOXO
CCR
ATP Citrate Lyase
p62
Hydroxylase
IFNAR
Pim
IDO
Glucocorticoid Receptor
Stearoyl-CoA Desaturase (SCD)
Lipid
SGK
c-Kit
ROR
Amino Acids and Derivatives
PAFR
DUB
Protease
Complement System
S1P Receptor
CAT
DYRK
Photosensitizer
Rho
PAK
AIM2
Platelet aggregation
IRAK
PGK1
ADC Cytotoxin
BTK
Monocarboxylate transporter
FXR
FABP
Bradykinin Receptor
Cadherin
Norepinephrine
STING
GluCls
PKM
MIF
P2X Receptor
GlyT
Somatostatin
Aminopeptidase
Urea Transporter
ASK
Methionine Adenosyltransferase (MAT)
Cuproptosis
Discoidin Domain Receptor (DDR)
DHFR
Tie-2
LDLR
Smo
Glutathione reductase
Acyltransferase
Adenosine Deaminase
PROTACs
stilbene oxidase
CD38
NR4A
ABC Transporter
DNA
ribosome
CRISPR/Cas9
Sigma receptor
HER
Advanced Glycation End Products
YAP
Necroptosis
OCT
Hck
RANKL/RANK
MT Receptor
Na-K-Cl cotransporter
ACK1
DNA Methyltransferase
Dynamin
P2Y Receptor
Lipase
Cell Cycle Arrest
Glucokinase
MTH1
Glucagon Receptor
DPP-4
OAT
MNK
RSV
c-Fms
Y Box Binding Protein 1
gp120/CD4
Progesterone Receptor
ASCT
NAMPT
cAMP
CPT
PAI-1
Melanocortin Receptor
Keywords
自由基清除剂药物发现氧化应激心血管保护小分子调节剂神经保护抗氧化研究抗氧化通路抗氧化酶抗氧化剂抗氧化化合物库抗氧化抗炎激活剂活性氧化合物库高通量筛选Small molecule modulatorSmall molecule compoundsROS清除剂ROS scavengerReactive oxygen speciesOxidative stressInhibitorHigh-throughput screeningFree radical scavengerDrug discoveryCompound libraryCancerAntioxidant researchAntioxidant pathwayAntioxidant enzymeAntioxidantAnti-agingActivator
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