mic 17

MtTMPK-IN-5 (compound 17) is a highly effective inhibitor of M. tuberculosis thymidylate kinase (Mtb TMPK), demonstrating remarkable enzyme inhibitory activity with an IC50 value of 34 μM. Additionally, MtTMPK-IN-5 exhibits notable activity against M. tuberculosis, as evidenced by a minimum inhibitory concentration (MIC) of 12.5 μM. Given its potent properties, MtTMPK-IN-5 serves as a valuable tool for tuberculosis research [1].

Antibacterial agent 105 (Compound 17) 是一种喹诺酮类的 Phenanthrolinic 类似物。Antibacterial agent 105 对结核分枝杆菌表现出抗菌活性，MIC90值为2.64 μM。此外，Antibacterial agent 105 对不同种类的菌种都表现出抗菌活性，对M. smegmatis,M. aurum,M. marinum,BCG,E. aerogenes 和S. aureus 的 MIC90值分别为 11.18, 11.18，0.70，1.40，44.70 和 22.35 μM。

Antitubercular agent-17 (Compound 8a) 是一种抗结核剂，对 M. tuberculosisH37Rv、Spec. 192、Spec 210 和 Spec. 800 的 MIC 值分别为 2、2、2 和 128 μg ml。Antitubercular agent-17 表现出高选择性的抗分支杆菌效果。

LfcinB 17-28 TFA，牛乳铁蛋白(LfcinB)的片段，展现出较弱的抗菌活性，其对E. coli的最小抑菌浓度(MIC)为200 μM。